TBZE-029 structure Common Name TBZE-029 CAS Number 246148-68-5 Molecular Weight 356.314 Density N/A Boiling Point N/A Molecular Formula C16H9F5N2S Melting Point N/A MSDS N/A Flash Point N/A Use of TBZE-029 TBZE-029 is a selective inhibitor of the replication of several ...
6 TBZE-029, drug-resistant coxsackievirus B3 (CVB3) was selected. Genotyping ofD7 resistant clones lead to the identification of 3 amino acid mutations in the non-structural 8 protein 2C, clustered at amino acid positions 224, 227 and 229 immediately downstreamE9 of the NTPase/helicase motif ...
TBZE-029 {1-(2,6-difluorophenyl)-6-trifluoromethyl-1H,3H-thiazolo[3,4-a]benzimidazole} is a novel selective inhibitor of the replication of several enteroviruses. We show that TBZE-029 exerts its antiviral activity through inhibition of viral RNA replication, without affecting polyprotein process...
TBZE-029{1-(2,6-difluorophenyl)-6-trifluoromethyl-1H,3H-thiazolo[3,4-a]benzimidazole}isanovelselectiveinhibitorofthereplicationofseveralenterovirusesWeshowthatTBZE-029exertsitsantiviralactivitythroughinhibitionofviralRNAreplication,withoutaffectingpolyproteinprocessingToidentifytheviraltargetofTBZE-029,drug-resist...