Iodine Mediated Nitrosation of Imidazo[1,5-a]N-heteroarenes using TBN (tBuONO) ReagentNitrosationTBNIodineImidazo[15-a]N-heteroarenesAn iodine mediated regio-selective nitrosation of imidazo[1,5-a]N-heteroarenes is reported using TBN as nitroso source. This method afford synthetically useful and ...
In this process, t BuONO is an efficient nitration and oxidation reagent while TEMPO is believed to act as a mild oxidant and a novel reagent to promote the Nef reaction that is accomplished under mild and neutral conditions. As a further aspect, the ( E )-4-oxo-but-2-enals thus ...