Polymer-supported organocatalystsAlthough its intriguing features, such as uniform functionalization through the entire beads and a very high-loading capacity are suitable candidates for solid-phase synthesis and reagent-scavenging, the use of Rasta resin as support for organocatalysis has been little ...
Robust, reliable, scalable From grams in research through to multi kilogram quantities in production campaigns.In general. This resin was developed to perform in a manner similar to that of the well-established catalyst, while facilitating reagent handling and simplifying workup, product isolation, an...
In this paper, we prepared a novel solid base catalyst SBA-15-pr-TBD by immobi...
base catalystorganosilicon compoundsThe ring opening of N-tosylaziridines with silylated nucleophiles catalyzed by 1,5,7-triazabicyclo[4,4,0]dec-5-ene (TBD) afforded the corresponding β-functionalized sulfonamides in excellent yields under mild reaction conditions. GRAPHICAL ABSTRACT...
The catalyst could be utilized with similar results for two further cycles (reaction: 68%; first recycle: 66%; second recycle: 63%). In conclusion, we have reported the use of a solid base easily prepared by anchoring the guanidine TBD to mesoporous silica MCM-41 as efficient and reusable...
1,5,7-Triazabicyclo[4.4.0]dec-5-ene (TBD), a bicyclic guanidine base, has been found to be an excellent catalyst for Michael and Michael-type reactions. A wide variety of Michael donors and acceptors can participate in these reactions using 10–20mol% of TDB. These reactions are mild, ...
Base catalystguanidineorganocatalystorganosilicon compoundstrifluoromethylationTrifluoromethylation of carbonyl compounds using (trifluoromethyl) trimethylsilane catalyzed by 1,5,7-triazabicyclo[4,4,0]dec-5-ene (TBD) afforded the corresponding 伪-trifluoromethyl alcohols in good to excellent yields under mild ...
The catalyst was reused several times without significant loss in activity.doi:10.1007/s11164-016-2755-9Karmakar, BikashNandi, RajeshSpringer NetherlandsResearch on Chemical Intermediates
basecatalystguanidineorganocatalystpolymercatalystThe ring-opening of N-tosylaziridines with various acid anhydrides catalyzed by 5 mol % of 1,5,7-triazabicyclo[4,4,0]dec-5-ene (TBD) afforded the corresponding 尾-amino esters in excellent yields under mild reaction conditions. Polymer-supported ...
BasecatalystPolymercatalystGuanidinePolystyrene-supported TBD (PS-TBD) catalyzes cyanosilylation of both aldehydes and ketones using TMSCN to give the corresponding products in high yields. Imines were also converted into the desired 伪-cyanoanimes under the same conditions. PS-TBD was easily recovered ...