For postnatal TB, the treatment duration may be increased to 9 or 12 months. Ethambutol often is avoided in young children. Special considerations for drug therapy in HIV-infected patients include the following: Dose adjustments may be necessary [6, 7] Rifampin must be avoided in patients ...
Emerging drugs and regimens aim to shorten treatment duration and improve outcomes. This article reviews recent advancements in TB treatment regimens, diagnostics, and vaccines, emphasizing the importance of these innovations in addressing drug-resistant TB and improving global TB control efforts.Shyamala ...
Shorter versus standard duration of treatment has been explored extensively since approximately 2014. In three phase III trials, shorter TB treatment regimens were less effective than standard 6-month regimens. [168, 169, 170, 171, 172] In all of the trials, one of the standard treatment drugs...
This study found that patients coinfected with TB and HIV took longer to recover from TB, with an average treatment duration of 11 months compared to 8 months for other TB patients. However, other studies have reported different average durations, such as 8.30 months in Teng et al.'s study...
When it comes to TB treatment, "there's an urgent need for shorter-duration, more potent, and safer anti-TB agents that are not only effective against drug-susceptible TB but also drug-resistant TB," Takuva told attendees. Quabodepistat is a novel decaprenyl-phosphoryl-β-D-ribose-2'-...
Clinical Trials.gov ``Using biomarkers to predict TB treatment duration'' https://clinicaltrials.gov/ct2/show/NCT02821832 Accessed Nov, 17, 2016. Google Scholar [25] N.N. Chegou, J.S. Sutherland, S. Malherbe, et al. Diagnostic performance of a seven-marker serum protein biosignature for...
Such a regimen would simplify programmatic implementation, reduce treatment duration, and improve adherence. Bedaquiline and TBAJ-876 given orally or as long-acting injectables could potentially be used as pan-TPT regimens. Long-acting formulations of pan-TPT regimens, particularly those that can be...
MDR-TB treatment is often expensive, with treatment duration being 24 months or longer. Expenses associated with TB and MDR-TB treatment may be partially covered by health insurance for patients enrolled in one of the health insurance schemes in China. However, patients still have to pay ...
Introduction. The convergence of TB and HIV dual epidemics is a major public health challenge in Ghana as well as many developing countries. Treatment outcome monitoring is a vital part of the survei...
They also lacked knowledge about TB treatment duration (71.6%, 1253), the meaning of DOTS (directly observed treatment, short course) (26.0%, 455) and multidrug resistance (20.6%, 360). Antibiotics (79.7%, 1396) and cough syrup (75.0%, 1313) were commonly prescribed by providers despite ...