As hyperinflammation is associated with worse outcomes, HDT with an anti-inflammatory effect might improve outcomes by reducing tissue damage and thus the risk of permanent sequelae. Methods SMA-TB is a multicentre randomized, phase IIB, placebo-controlled, three-arm, double-blinded clinical trial (...
TIMING: Once the above risk assessment concludes that speaking up is the better option, then it is important to carefully think about the timing of speaking up. You might need more time to rethink the issue. You may benefit from getting more insights or views from colleagues, and develop you...
ofollow-up assessment was within a week of baseline assessment; 93.3% of adults completed trial and were included in analyses ocomparing lumbar spinal stenosis belt vs. lumbar support §mean improvement in walking distance 125 m vs. 167.1 m (not significant) ...
of which 1.5 million cases are fatal. Patients that are infected with HIV have a high risk of developing active TB, and HIV-TB co-infection is responsible for 20% of all TB-related deaths. Early diagnosis of active TB followed by treatment with rifampicin, isoniazid, and ethambutol and the...
A meta-analysis on the risk of TB for these factors yielded a pooled relative risk of 2.94 (95% CI: 1.89-4.59). Numerous studies show pathogenic impact of alcohol on the immune system causing susceptibility to TB among heavy drinkers. In addition, there are potential social pathways linking...