The researchers said in those with severe disease, the body was responding as if it was attacking a virus, enabling the bacteria to remain hidden and replicate unchallenged within cells. Not only is interferon-beta an ineffective weapon against bacteria, it can block the action of interferon gamm...
behaviour of the cells. They found that the presence of IL-17, the molecule that Th17 cells produce, reduces the growth of TB bacteria. This data confirms that Th17 cells are likely to have a protective role in humans and gives researchers a new focus for vaccine strategies. "This work un...
The present invention is based on a number of M.tuberculosis derived proteins and protein fragments which are induced during the latent stage of infection characterized by low oxygen tension in the microenvironment of the infecting TB-bacteria. The invention is directed to the use of these polypepti...
When a healthy person gets infected with TB, their immune system cells will usually wall off the infection and cause the TB bacteria to go into an inactive form that causes no symptoms and is not contagious; this is known as latent TB infection. It is possible to live with latent TB with...
New strains of drug-resistant bacteria with altered virulence have already emerged, exploiting precisely this weakness by targeting immunodeficient patients. Bioinformatics and genetics help identify a dangerous strain of TB pathogens Researchers currently identify seven to eight major M. tuberculosis lineages...
, Laneke Luies1 , Du Toit Loots1 and Aurelia A. Williams1* Open Access Abstract Background The synergy between the human immunodeficiency virus (HIV) and Mycobacterium tuberculosis dur- ing co-infection of a host is well known...
Also, patients with bone TB are generally not contagious because the disease spreads through coughed up active virus particles unless you come in contact with a patient’s pus. Another important point to remember is that bone TB may affect the bone marrow, so timely and complete course of trea...
The synergy between the human immunodeficiency virus (HIV) and Mycobacterium tuberculosis during co-infection of a host is well known. While this synergy is known to be driven by immunological deterioration, the metabolic mechanisms that contribute to th
common cold (virus) and with a sinus infection (bacteria). A doctor may use the presence of other symptoms (such as fever or body aches), the length of the illness, and certain lab tests to determine if an illness is due to a virus, bacteria, or some other pathogen or disease ...
Acid-fast bacteria fluoresce yellow-orange. Both fluorescence microscopy and Ziehl-Neelsen staining had 100% specificity using the Xpert MTB/RIF as the reference test [32]. In addition, the former demonstrated higher sensitivity (84.5% vs 54.8%) and shorter reading time. Smear microscopy is a ...