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Ideal mixing in the bioreactor is difficult to achieve in practice, therefore a compromise between shear and mass transport must be made (Vunjak-Novakovic et al., 1999). For a functional tissue sample to be engineered in vitro, a uniform physico-chemical environment must be maintained over time...
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This observation seems coherent with the plausible evolutionary path of taylorellae reported by Gosh et al., [13] which suggests that the evolution of the taylorellae genome is mainly based on a reduction in size, with very few new gene acquisitions since taylorellae’s separation from the ...
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