Medical Definition Tay-Sachs disease noun ˈtā-ˈsaks- variants or Tay-Sachs : a hereditary disorder of lipid metabolism typically affecting individuals of eastern European Jewish ancestry that is marked by the accumulation of lipids especially in nerve cells of the brain due to a deficie...
The meaning of TAY-SACHS DISEASE is a hereditary disorder of lipid metabolism typically affecting individuals of eastern European Jewish ancestry that is marked by the accumulation of lipids especially in nerve cells of the brain due to a deficiency of h
Define Tay-Sachs' disease. Tay-Sachs' disease synonyms, Tay-Sachs' disease pronunciation, Tay-Sachs' disease translation, English dictionary definition of Tay-Sachs' disease. n. A hereditary disease that affects young children almost
Definition and Characteristics Autosomal recessive defect in the α-subunit of the dimeric β-hexosaminidases A (αβ) and also S (αα) leads to accumulation of ganglioside GM2 in the lysosomes especially of neuronal cells [1]. Together with Sandhoff’s disease and GM2-activator protein-defici...
a hereditary disorder of lipid metabolism occurring most frequently in individuals of Jewish descent in eastern Europe; accumulation of lipids in nervous tissue results in death in early childhood synonyms: Sachs disease, Tay-Sachs disease, infantile amaurotic idiocy see more Cite...
Tay–Sachs DiseaseSynonymsSynonymsβ-Hexosaminidase α-subunit deficiency; B-variant of the GM2-gangliosidosesDefinition and CharacteristicsDefinition and CharacteristicsAutosomal recessive defect in the α-subunit of thedoi:10.1016/B0-12-226870-9/01302-2C. Niesen...
A definition of the term "Tay-Sachs disease" is presented. It refers to the most severe of the lipid storage diseases. This disease is marked by neurological deterioration in the first year of life. A genetic abnormality on chromosome 15 causes the disease. The metabolic abnormality results in...
especially in the nerve cells of the brain. This ongoing accumulation causes progressive damage to the cells and leads to a neurodegenerative disease. The overall prevalence of TSD is estimated to be about one in 200,000 live births in the general population. A high prevalence is found in the...
The abbreviation TSD stands for Tay-Sachs Disease and is mostly used in the following categories: Medical, Genetics, Healthcare, Health Statistics, NVSS.Whether you're exploring these categories or simply seeking a quick definition, this page provides comprehensive information on TSD.Related...
Define Tay Sachs disease. Tay Sachs disease synonyms, Tay Sachs disease pronunciation, Tay Sachs disease translation, English dictionary definition of Tay Sachs disease. n. A hereditary disease that affects young children almost exclusively of eastern Eu