2016. Tau in physiology and pathology. Nat Rev Neurosci, 17, 5-21. WANG, Y., MARTINEZ-VICENTE, M., KRUGER, U., KAUSHIK, S., WONG, E., MANDELKOW, E. M., CUERVO, A. M. & MANDELKOW, E. 2009b. Tau fragmentation, ag
The polarized distribution of tau into the axonal compartment of neurons is determined by multiple mechanisms. In addition, part of tau is actively released into extracellular space. Besides stabilizing microtubules, regulating their dynamic instability and supporting axonal transport, tau can interact with...
Tau in physiology and pathology. Nat. Rev. Neurosci. 17, 5–21 (2016). Article PubMed Google Scholar Binder, L. I., Frankfurter, A. & Rebhun, L. I. The distribution of tau in the mammalian central nervous system. J. Cell Biol. 101, 1371–1378 (1985). Article PubMed CAS Google...
1. Chang, C. -W., Shao, E., & Mucke, L. (2021). Tau: enabler of diverse brain disorders and target of rapidly evolving therapeutic strategies. Science, 371(6532), eabb8255. 2. Wang, Y., & Mandelkow, E. (2016). Tau in physiology and pathology. Nature Reviews Neuroscience, 17(...
Mandelkow Tau in physiology and pathology Nat. Rev. Neurosci., 17 (2016), pp. 5-21 CrossrefGoogle Scholar Wang et al., 2018 J. Wang, J.-M. Choi, A.S. Holehouse, H.O. Lee, X. Zhang, M. Jahnel, S. Maharana, R. Lemaitre, A. Pozniakovsky, D. Drechsel, et al. A ...
Mandelkow Tau in physiology and pathology Nat. Rev. Neurosci., 17 (2016), pp. 5-21 CrossrefGoogle Scholar 6 M.M. Alhadidy, N.M. Kanaan Biochemical approaches to assess the impact of post-translational modifications on pathogenic tau conformations using recombinant protein Biochem. Soc. Trans...
Wang Y , Mandelkow E .Tau in physiology and pathology[J]. Nat Rev Neurosci, 2016,17(1):5-21. DOI: 10.1038/nrn.2015.1 . 返回引文位置Google Scholar 百度学术 万方数据 [11] Huang Y , Mucke L .Alzheimer mechanisms and therapeutic strategies[J]. Cell, 2012,148(6):1204-1222. DOI: 10....
Tau in physiology and pathology. Nat. Rev. Neurosci. 17, 5–21 (2016). 52. Tai, C. Y. et al. Synatically preference anti-tau antibodies reduce in vitro tau seeding and in vivo neuronal loss. Alzheimer's Dement. 16(Suppl. 9), e042368 (2020). 53. Jicha, G. A., Bowser, R....
Wang Y, Mandelkow E (2016) Tau in physiology and pathology. Nat Rev Neurosci 17: 5–21 https://doi.org/10.1038/nrn.2015.1 21. Martin L, Latypova X, Terro F (2011) Post-translational modifications of tau protein: implications for Alzheimer's disease. Neurochem Int 58: 458–471 https:/...
Tau in physiology and pathology. Nat. Rev. Neurosci. 17, 5–21 (2016). Article PubMed Google Scholar Tai, C. Y. et al. Synatically preference anti-tau antibodies reduce in vitro tau seeding and in vivo neuronal loss. Alzheimer’s Dement. 16(Suppl. 9), e042368 (2020). Google ...