From a batch system perspective, turnaround time can be considered the time taken in batch formation and printing of results. The concept of turnaround time overlaps with lead time and contrasts with the concept of cycle time. Turnaround time is expressed in terms of units of time for a ...
In a world full of Tit for Tats, any of these Ominous Ms can lead to a catastrophic cycle. I asked Stable Diffusion for an Evil Letter M in a Tophat Say two Tit for Tats run into each other in real life. Both are immediately nice to one another and begin to reciprocate said nice...
HIV-1 transcription activator protein Tat is phosphorylated in vitro by CDK2 and DNA-PK on Ser-16 residue and by PKR on Tat Ser-46 residue. Here we analyzed Tat phosphorylation in cultured cells and its functionality. Mass spectrometry analysis showed pr
for the first time, describe the mechanistic insights underlying HIV-1 Tat-mediated lysosomal dysfunction and possible restoration intervention strategies, such as lysosomal protection, that could be developed as a potential therapeutic target(s)
Real-Time PCR was performed on the LightCycler® 96 (Roche) and used SYBR green detection with the following thermal profile: segment 1–1 cycle: 95 °C for 10 minutes, segment 2–40 cycles: 95 °C for 15 seconds followed by 60 °C for 1 minute. All data from PCR ...
IMVs were isolated as described17, except that: (i) lysozyme was used at 1 mg/mL when making spheroplasts; (ii) the EDTA/lysozyme incubation time to make spheroplasts was 30 min; (iii) the French press was set to 16,000 psi for making IMVs; and (iv) the three step ...
with colors indicating relative expression levels. Real-time PCR analysis of miR-7 expression in the brains of uninfected and SIV+ (b) or HIV+ (c) subjects.dIn situ hybridization demonstrating increased expression of miR-7 in the astrocytes of SIV-infected macaques. *p < 0.05 vs control...
CD4+ T cells, CD8+ T cells and CD4+/CD8+ T-cell ratio over time were analysed according to anti-Tat humoral and cellular responses in a longitudinal regression analysis for repeated measures using a mixed model with random-effects; N = 95 anti-Tat Ab−, 23 anti-Tat Ab+, 40 infrequen...
Data, expressed as mean ± SEM, are normalized to control and represent an average of three independent experiments (n = 2 each time point each experiment). *p < 0.01, **p < 0.001 vs control (ANOVA and Tukey’s test). b Cortical neurons were exposed to Tat (100 ...
tail withdrawal was measured on day 9 before acute cumulative morphine injections. The distal 1/3 of the mouse-tail was immersed in the warm-water bath and the latency for the mouse to remove its tail was measured. The duration of time the tail remained in the water bath was counted as ...