The invention discloses a method for detecting single nucleotide polymorphism (SNP) of a cattle TAS1R3 gene. The method comprises the following steps of: performing PCR amplification on the cattle TAS1R3 gene by
The protein encoded by this gene is a G-protein coupled receptor involved in taste responses. The encoded protein can form a heterodimeric receptor with TAS1R1 to elicit the umami taste response, or it can bind with TAS1R2 to form a receptor for the sweet taste response. ...
R. Engineering hybrid genes without the use of restriction enzymes: gene splicing by overlap extension. Gene 77, 61–68 (1989). 61. Shimizu, M., Goto, M., Kawai, T., Yamashita, A. & Kusakabe, Y. Distinct human and mouse membrane trafficking systems for sweet taste receptors t1r2 and...
Variation in the TAS2R31 bitter taste receptor gene relates to liking for the nonnutritive sweetener Acesulfame-K among children and adults Authors: Nuala Bobowski, Danielle Reed, Julie A. Mennella CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tast...
Abstract The taste receptor type I (Tas1R) family consists of three G protein-coupled receptors (T1R1, T1R2, and T1R3) that form heterodimers recognizing sweet compounds (T1R2/T1R3) or amino acids (T1R1/T1R3). These receptors are nutrient sensors that facilitate appropriate physiological resp...
Conclusion: TAS1R2, TAS1R3, and TAS2R38 gene expression levels were decreased in the Delta variant compared to the Omicron BA.1 variant in the studied groups. These results provided a significant clue for the temporary taste loss, especially in patients infected with...
We measured Tas1r3 gene expression, transcript size, and T1R3 immunoreactivity in the taste tissue of two inbred mouse strains with different Tas1r3 haplotypes and saccharin preferences. The results of these experiments suggest that the polymorphisms associated with saccharin preference do not act by...
Inoue,M,Reed,DR,Li,X,Tordoff,MG,Beauchamp,GK,Bachmanov,AA.Allelic variation of the Tas1r3 taste receptor gene selectively affects behavioral and neural taste responses to sweeteners in the F2 hybrids between C57BL/6ByJ and 129P3/J mice.The Journal of Neuroscience. 2004...
Sweet taste receptor gene TAS1R3 polymorphisms related to food preferences, biochemical parameters and body compositiondoi:10.1016/j.nut.2018.03.022Perna S.Nichetti M.Moncaglieri F.Avanzato I.Spadaccini D.Rondanelli M.Nutrition
Inter- and intra-species differences in consumption of sweet tastants formed during the evolution of vertebrates are thought to be due to polymorphism of the Tas1r3gene encoding T1R3, a sweet taste...doi:10.1134/S0022093018030079Murovets V. O....