Targeting Aging with Metformin (TAME)doi:10.1007/978-3-319-69892-2_400-1Padki, Milind M.Vetek - the Movement for Longevity and Quality of Life (US Branch)Stambler, IliaBar Ilan University
其实很多抗衰药物都进行过人体临床,但以二甲双胍作为主体的TAME,却是有史以来第一个靶向衰老的人体临床实验,所以对整个抗衰圈乃至全世界来说都意义非凡。 TAME是“二甲双胍靶向衰老”(Targeting Aging with Metformin)的英文首字母缩写,单词本身又有着 “驯服、圈养”的含义。自然 发布于 2023-07-04 18:45・IP ...
The first is that the efficacy of metformin awaits confirmation from large sample trial data such as from the Targeting Aging with Metformin (TAME) trial. Our calculated results will naturally differ if such results lead to different estimates than in ref. 28. The second is that the key ...
TAME is designed on the premise that geroscience-based therapeutics will affect multiple disease outcomes. Extensive biological data show that metformin targets the biology of aging, and epidemiologic and some clinical trial data show that it prevents multiple age-related diseases. TAME will randomize ...
Effect of metformin plus tyrosine kinase inhibitors compared with tyrosine kinase inhibi tors alone in patients with epidermal growth factor receptor- mutated lung adenocarcinoma: a Phase 2 randomized clinical trial. JAMA Oncol. 2019;5:e192553. doi:10.1001/jamaoncol.20 19.2553 22. Charbgoo F...
Targeting Aging with Metformin (TAME)doi:10.1007/978-3-030-22009-9_400Padki, Milind M.Vetek - the Movement for Longevity and Quality of Life (US Branch)Stambler, IliaBar Ilan University
Effect of metformin plus tyrosine kinase inhibitors compared with tyrosine kinase inhibi tors alone in patients with epidermal growth factor receptor- mutated lung adenocarcinoma: a Phase 2 randomized clinical trial. JAMA Oncol. 2019;5:e192553. doi:10.1001/jamaoncol.20 19.2553 22. Charbgoo F...