Targeted next generation sequencing (NGS) focuses on specific regions of interest in the genome. With targeted NGS, researchers can target specific genes, coding regions, or even chromosomal segments at deeper coverage than alternative sequencing methods, obtaining fast, accurate, and precise genomic in...
Targeted Next Generation Sequencing (NGS) to classify melanocytic neoplasmsambiguousmelanomamolecularnext generation sequencingSpitzThis study piloted a pan‐solid‐tumor next generation sequence (NGS)‐based laboratory developed test as a diagnostic aid in melanocytic tumors. 31 cases (4 "epithelioid" nevi...
NGSTargeted captureADMERare variantsPhenotypic differences in drug responses have been associated with known pharmacogenomic loci, but many remain to be characterized. We therefore developed next-generation sequencing (NGS) panels to enable broad and unbiased inspection of genes that are involved in ...
Ion Torrent next-generation sequencing systems Ion AmpliSeq panels are compatible with both the Ion GeneStudio S5 System and the Ion Torrent Genexus System to deliver ease of use, automation capabilities, and rapid NGS test results in as little as 24 hours....
Amplicon sequencing is a type of targeted next generation sequencing that uses PCR to create DNA sequences called amplicons. It is simple and fast with a variety of applications.What is amplicon sequencing? Amplicon sequencing is a method of targeted next generation sequencing (NGS) that enables ...
Targeted Next-Generation Sequencing for Clinical Diagnosis of 561 Mendelian Diseases.doi:10.1371/journal.pone.0133636Targeted next-generation sequencing (NGS) is a cost-effective approach for rapid and accurate detection of genetic mutations in patients with suspected genetic disorders, which can facilitate...
Mutational profiling by targeted next-generation sequencing (NGS) might further improve risk stratification. Patients with stage IV squamous cell carcinoma of the oropharynx and hypopharynx who had been enrolled in a randomized phase III trial (ARO-0401) comparing two regimens of cCRTX and from whom...
The Ion Torrent immunology research portfolio enables a multi-dimensional research approach to repertoire sequencing and immune response. Each targeted next-generation sequencing (NGS) assay is powered by the accuracy and sensitivity of Ion Torrent technology to help discover more from wit...
Targeted sequencing is a technique that uses NGS to target specific genes, coding regions of the genome, or chromosomal segments for rapid identification and analysis of genetic mutations.
Targeted next-generation sequencing (NGS) on 189 genes was performed to screen for RP causative mutations in the two families. Two biallelic mutations in EYS, p.[R164*];[C2139Y] and p.[W2640*];[F2954S], were identified in the two families, respectively. EYS p.R164* and p.F2954S ...