On the flip side, the high non-specific protein affinity results in significant off-target effects, meaning biological outcomes that are caused by interactions other than that on the targeted gene [18], [19]. Biological investigations and the clinical evaluation of mipomersen and other antisense ...
Cancers are also different in their survival rates, which are assessed based on the chances that a cancer patient stays alive, usually after five years of diagnosis. Some skin cancers like non-melanoma skin cancer have a 99.9% five-year survival rate, meaning that less than 1 person in 100...