Faculty of 1000 evaluation for Quantitative proteomics identifies the Myb-binding protein p160 as a novel target of the von Hippel-Lindau tumor suppressor.Jonathan Gleadle
and therefore endocrine-resistant disease may constitute up to one- quarter of all breast cancers.3 The Cancer Genome Atlas (TCGA) consortium reported that most dominant feature of Luminal/ER- positive breast cancers is increased mRNA and protein levels of ESR1, GATA3, FOXA1, XBP1 and MYB. Mo...
Schulz C, Gomez Perdiguero E, Chorro L, Szabo-Rogers H, Cagnard N, Kierdorf K, Prinz M, Wu B et al (2012) A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science 336(6077):86–90. doi:10.1126/science.1219179 Article CAS PubMed Google Scholar Hashimoto ...
IPI00005024 Q9BQG0 Isoform 1 of Myb-binding protein 1Aa 1,012 149,731 26 16.8 0.74 0.37 0.64 0.58 0.19 VKKD 0.93, LKAD 0.91 Nucleoli IPI00006702 Q81ZL8 Isoform 1 of proline-, glutamic acid-, and leucine-rich protein 1 160 120,879 4 3.9 0.69 0.35 0.52 0.24 IKEE 0.94, LKLD 0.91...
Chemical biology strategies for directly perturbing protein homeostasis including the degradation tag (dTAG) system provide temporal advantages over genetic approaches and improved selectivity over small molecule inhibitors. We describe dTAGV-1, an exclu
The tom-1 gene has two promoters, one of which is Myb-inducible. tom-1 is expressed at elevated levels in AMV-transformed as well as in E26-transformed myeloid cells. We show that tom-1 activation by v-Myb does not require de novo protein synthesis and that the Myb-inducible tom-1 ...
Mm.479 2.9 MYBL1 v-myb myeloblastosis oncogene homolog-like 1 Mm.18810 2.8 ZFP422 zinc finger protein 422 Mm.45039 2.1 LRRFIP1 leucine-rich repeat in flii-interacting protein 1 Mm.925 2.0 TFDP1 transcription factor dp1 Others Mm.246318 2.5 EIG180 ethanol-inducble gene 180 Mm.62886 2.0...
In mammalian cells, WTAP was shown to bind the Wilm’s tumor 1 protein, which is critical for embryonic development.45., 46. Interestingly, WTAP levels are closely related to those of METTL3, which was shown to regulate WTAP homeostasis.47 Regarding the other MACOM complex subunits, VIRMA ...
Analysis of fractalkine receptor CX3CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol. Cell. Biol. 20, 4106–4114 (2000). CAS PubMed PubMed Central Google Scholar Sehgal, A. et al. The role of CSF1R-dependent macrophages in control of the ...
Nymphaea (waterlily) is known for its rich colors and role as an important aquatic ornamental plant globally. Nymphaea atrans and some hybrids, including N. ‘Feitian 2,’ are more appealing due to the gradual color change of their petals at different fl