A novel method of delivering drugs and diagnostics across the blood-brain barrier or blood-nerve barrier is disclosed. Drugs or diagnostic agents are incorporated into nanoparticles which have been fabricated in conventional ways. These nanoparticles are then coated with additional surfactant and given ...
Chinese medicine is a complex system guided by traditional Chinese medicine (TCM) theories, which has proven to be especially effective in treating chronic and complex diseases. However, the underlying modes of action (MOA) are not always systematically investigated. Herein, a systematic study was ...
v.,HJ Fehling - 《Journal of Experimental Medicine》 被引量: 92发表: 1997年 Insulin Induces REDD1 Expression through Hypoxia-inducible Factor 1 Activation in Adipocytes REDD1 (regulated in development and DNA damage responses) is essential for the inhibition of mTORC1 (mammalian target of ...
Multi-target regulatory mechanism of Yang Xin Tang − a traditional Chinese medicine against dementia Tung Yan Lo, Anthony Siu Lung Chan, Suet Ting Cheung, Lisa Ying Yung, Manton Man Hon Leung & Yung Hou Wong Chinese Medicine volume 18, Article number: 101 (2023) Cite this ...
An Omics Perspective on Cancer Research || Translational Medicine: Application of Omics for Drug Target Discovery and Validation Introduction:Atrial Fibrillation (AF) is the most prevalent cardiac arrhythmia in the United States. Effective, safe, and durable therapeutic interventions... Cho,CS William ...
Today’s Geriatric Medicine Vol. 6 No. 4 P. 6 Current FDA-approved medications that help to manage Alzheimer’s disease (AD) symptoms and slow its progression include cholinesterase inhibitors (CIs) and N-methyl-D-aspartate antagonists (NMDAs).1 ...
Lakey, in Encyclopedia of Tissue Engineering and Regenerative Medicine, 2019 Immunosuppression Treatment Immunosuppression used during the Edmonton protocol demonstrated the importance of using strong immunosuppressive regimens in seven patient clinical trials in maintenance of the islet graft. The Edmonton ...
Latest Research and Reviews Small molecule APOL1 inhibitors as a precision medicine approach for APOL1-mediated kidney disease Apolipoprotein L1 genetic variants contribute to a subtype of proteinuric kidney disease referred to as APOL1-mediated kidney disease (AMKD). Here the authors report the disco...
"Our research team will recruit volunteers to conduct large-scale multi-center joint clinical trials in the future to further verify the treatment target," Qiao said. The research was published in the journal Nature Medicine.
Department of Medicine, Graduate School, Kyung Hee University, Seoul, Republic of Korea Seung-Hun Kang Futuristic Animal Resource & Research Center (FARRC), Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju, Republic of Korea ...