Genome-wide association studies (GWAS) have identified more than 170 breast cancer susceptibility loci. Here we hypothesize that some risk-associated variants might act in non-breast tissues, specifically adipose tissue and immune cells from blood and spleen. Using expression quantitative trait loci (e...
BaxterPublished: July 17, 2020Getty Images Share on Facebook Share on Twitter Minnesota based Target Corporation announced today that starting August 1st, customers will be required to wear mask while shopping in any of their nationwide stores. Getty Images Target is the latest to implement this ...
Robert Baxter Epigenetics and Transcription Laboratory, Melanie Swan Memorial Translational Centre, Sci-Tech, University of Canberra, Canberra, Australian Capital Territory, Australia Desmond Yip Department of Medical Oncology, The Canberra Hospital, Canberra, Australian Capital Territory, Australia Desmond Yip...
JAK2V617F has served as a target for the development of a number of tyrosine kinase inhibitors (Baxter et al. 2005; James et al. 2005; Kralovics et al. 2005; Levine et al. 2005). These novel agents have been tested in phases I, II, and III studies and as a class have been ...
41. Modhiran N, Watterson D, Blumenthal A, Baxter AG, Young PR, Stacey KJ. Dengue virus NS1 protein activates immune cells via TLR4 but not TLR2 or TLR6. Immunol Cell Biol. 2017;95(5):491–5. 42. Glasner DR, Ratnasiri K, Puerta-Guardo H, Espinosa DA, Beatty PR, Harris E. ...
Phone: 86-431-88796520; Fax: 86-431-88796975; E-mail: miaolining55@163.com; or Lu Cai, KCHRI, Department of Pe- diatrics, University of Louisville, 570 South Preston Street, Baxter I, Suite 304F, Louisville, KY 40202. Phone: 502-852-2214; Fax: 502-852-5634; E-mail: l0cai001...
Baxter, and M. James, Structure of recombinant human renin, a target for cardiovascular-active drugs, at 2.5 A resolution. Science, 1989. 243(4896): p. 1346-1351.Sielecki AR, Hayakawa K, Fujinaga M, Murphy ME, Fraser M, Muir AK, Carilli CT, Lewicki, J, Baxter JD, James MN. ...
Tissue mononuclear phagocytes (MNP) are specialised in pathogen detection and antigen presentation. As such they deliver HIV to its primary target cells; CD4 T cells. Most MNP HIV transmission studies have focused on epithelial MNPs. However, as mucosal trauma and inflammation are now known to be...
as promising candidates for future therapies using synthetic miRNA mimics and inhibitors. The first miRNA therapeutic for the treatment of humane hepatitis C virus is currently in phase II clinical trials, underscoring the potential of miRNA-based therapy (Janssen et al.2013; Chakraborty et al.2021...
Research project grants from Roche Palo Alto, AstraZeneca Limited, Cyclacel Limited and Baxter Biosciences Consultancy for Roche Palo Alto and Baxter Biosciences Authors' contributions CT, NA, Writing manuscript, Figures, Tables. Writing manuscript, Tables. MS, RJU, FT, Editing manuscript. All author...