The International Diabetes Federation (IDF) has launched a new global guideline on the management of type-2 diabetes which sets target blood glucose levels (HbA1c) at below 6.5 per cent.This is much tougher than the 7.4 per cent target in the qualityMA Healthcare Ltd...
**based on duration of diabetes, age/life expectancy, comorbid conditions, known CVD or advancedmicrovascular complications, hypoglycemia unawareness, and individual patient considerations.†Postprandial glucose may be targeted Blood sugar target levels for nonpregnant adults with diabetes coincide with A1C...
CGM provides a full range of glucose parameters including TIR, which fills the blind spot of HbA1C and traditional SMBG monitoring and is one of the future trends of diabetes metabolic monitoring. As a new indicator, TIR is a simple and intuitive metric that provides information about the ...
Stronger association of triglyceride glucose index than the HOMA-IR with arterial stifness in patients with type 2 diabetes: a real-world singlecentre study. Cardiovasc Diabetol. 2021;20(1):82. Article CAS PubMed PubMed Central Google Scholar Cho YK, Lee J, Kim HS, et al. Triglyceride ...
plays a significant role in the cause of the disease as the body loses the ability to regulate blood glucose. Currently available drugs work by stimulating alternative ways for the body to use or eliminate glucose. There are no approved drugs available to address the causes of type 2 diabetes...
Augmented glucose metabolism promotes mitochondrial activity by prompting AMP levels that disturb the ATP: AMP ratio resulting in the activation of the AMPK leading to phosphorylation of TSC2 which enhances the GAP activity of TSC2 for the Rheb to repress the mTORC1 activity.68 Moreover, AMPK ...
We studied examine the visceral fat area(VFA) target for improving multiple risk factor clustering in patients with impaired glucose tolerance and mild type 2 diabetes mellitus who were not taking medication. Risk factors were defined as systolic blood pressure≥140 mmHg and/or diastolic blood pressu...
Type 2 Diabetes is a major risk factor for Alzheimer's disease and dementia and the concept that Alzheimer's is fundamentally a metabolic disease that results in progressive impairment in the brain's capacity to utilize glucose and respond to insulin/insulin like growth factor stimulation has ...
Therefore, visit-to-visit HbA1c variability may represent, at the moment, a good option for evaluating the glucose variability over a given long interval of time [31]. A number of intermediate pathways and mechanisms have been proposed as possible mediators of the GV- induced damage to the ...
Molecular Epidemiology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden Erik Ingelsson Stanford Diabetes Research Center, Stanford University, Stanford, CA, USA Erik Ingelsson The Centre of Public Health Sciences, University of Iceland, Reykjavik, Icelan...