CD38, LRPAP1, NTRK2, Beta-NGF, BMP-4, BCAN, VWC2, CDH3, CDH6, CPA2, CPM, CTSS, CADM3, CD200R1, CLM-1, CLM-6, CNTN5, CLEC1B, CLEC10A, CRTAM, Dkk-4, CTSC, ADAM 22, ADAM 23, DRAXIN, EPHB6, EFNA4, DDR1, NEP, UNC5C, NBL1, NCAN, Nr-CAM, NRP2, N-CDase, ...
Interestingly, deletion of the Nrp-1 gene in macrophages resulted in the retention of macrophages in normoxic areas, subsequently leading to diminished pro-angiogenic and immunosuppressive functions. This study concluded that localization of macrophages, regulated by Sema3A/Nrp-1 signaling, plays an ...
The Uqcrfs1´/´ CD4+ T cells failed to induce IL-2 and were less activated (reduced CD69 and CD25 markers) in response to anti-CD3 and anti-CD28 stimulation. Hence, mitochondria targeting to immune cells (e.g., T cell, natural killer cells) by NP-systems can be a promising ...
CAR T-cell therapy has reported significant clinical response, with up to 90% complete remission rates in acute lymphoblastic leukemia targeting the B-cell antigen CD19 [28]; it has also shown high efficacy in the treatment of leukemia using CD22-directed CAR T-cells [29]. Despite successful...
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The setting used for the searches were ATAD2, SPINT3, CDKN1c, and CLDN8; cancer type: Breast. 3. Results 3.1. SUMOylation Suppresses PR Transcriptional Activity in a Promoter Dependent Manner Downstream of aa165, PR-A and PR-B share post-translational modifications sites including ones for...
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