Tamoxifen-inducible podocyte-specific iCre recombinase transgenic mouse provides a simple approach for modulation of podocytes in vivo. Genesis 48, 446-451 (2010).Wang J, Wang Y, Long J, Chang BH, Wilson MH, Overbeek P, Danesh FR. Tamoxifen-inducible podocyte-specific iCre recombinase ...
Recent development of the tamoxifen-inducible Cre-ER T2 offers both cell type-specific and temporal control of conditional gene inactivation. As an example, we describe the design and step-wise construction of a Cre-ER T2 knock-in allele at the Pax7 locus using the recombineering method – ...
Generation of a transgenic mouse model with chondrocyte-specific and tamoxifen-inducible expression of Cre recombinase Genesis, 45 (2007), pp. 44-50 Google Scholar 6 P. Soriano Generalized lacZ expression with the ROSA26 Cre reporter strain Nat Genet, 21 (1999), pp. 70-71 Google Scholar 7 ...
Novel caspase-suicide proteins for tamoxifen-inducible apoptosis. Genesis. 2008; 46 :530–536. doi: 10.1002/dvg.20426. [ Cross Ref ]Chu Y, Senghaas N, Koster RW, Wurst W, Kuhn R: Novel caspase-suicide proteins for tamoxifen-inducible apoptosis. Genesis 2008, 46:530-536....
Baicalein resensitizes tamoxifen-resistant breast cancer cells by reducing aerobic glycolysis and reversing mitochondrial dysfunction via inhibition of hypoxia-inducible factor-1α 来自 EBSCO 喜欢 0 阅读量: 64 摘要: Drug resistance is a major hurdle for the effectiveness of tamoxifen (TAM) to provide ...
TamoxifenEstrogenEstradiolIndirect evidence suggests that estrogen is involved in the etiology of breast cancer. Estrogen is also thought to modulate nitric oxide (NO) in human breast tumor tissue via regulation of inducible nitric oxide synthase (iNOS). Objectives of this study were to determine ...
Tamoxifen-inducible glia-specific cre mice for somatic mutagenesis in oligodendrocytes and Schwann cells ; [beta]1-integrin regulates neural progenitor maintenance through modulation of growth factor signaling /Dino Leone
By breeding with tdTomato reporter mice and initiating Cre activity through tamoxifen induction at distinct developmental time points, we show the Tfap2b lineage within the key neural crest-derived domains, such as the facial mesenchyme, midbrain, cerebellum, spinal cord, and limbs. Notably, the ...
630. Tamoxifen-Inducible Expansion of Murine Hematopoietic Stem Cells by Retroviral-Mediated Transfer of a HOXB4-ERT2 Fusion ProteinRNA transfectiondendritic cellcytotoxic T lymphocytesadoptive therapyvaccine therapymt is a cross-disciplinary biomedical journal devoted to publishing the most exciting advances...
One of the most frequently used lineage tracing approaches involves tamoxifen-inducible Cre ERT -LoxP systems. However, tamoxifen treatment can also promote effects independent of Cre recombinase activation, many of which have not been fully explored. To elucidate off-target effects of tamoxifen, male...