Accumulated genetic and epigenetic changes often activate the expression of oncogenes while silencing tumor suppressors during carcinogenesis. For example, malignant progression can be driven by an increasing number of secreted EVs that carry a truncated and oncogenic form of the epidermal growth factor r...
Hoffmann. Those stories are “Der Sandmann” (“The Sandman”), “Rath Krespel” (“Councillor Krespel”; Eng. trans. “The Cremona Violin”), and “Die Geschichte vom verlorenen Spiegelbilde” (“The Story of the Lost Reflection”). The opera was intended for the 1877–78 season at ...