In the ’80s, DuPont started marketing naltrexone as a treatment for alcoholism as it causes drinkers to feel none of the pleasant effects of alcohol yet all of the unpleasant effects. As you can imagine, the biggest issue was patient compliance. Naltrexone never really took off as a ...
Current treatments include cognitive behavioral therapy, replacement therapy (eg, methadone and buprenorphine), and antagonist therapy (eg, naltrexone). However, of this population, 40–60% will relapse following traditional treatment and rehabilitation within a year (McLellan et al, 2000). The ...
The α4β2 nAChR partial agonist varenicline, which was originally developed as a smoking cessation medication4, appears to be equally efficacious for reducing alcohol use6,7. Likewise, the mu opiate antagonist naltrexone is approved for treatment of opioid and alcohol abuse, but in some ...
Current treatments include cognitive behavioral therapy, replacement therapy (eg, methadone and buprenorphine), and antagonist therapy (eg, naltrexone). However, of this population, 40–60% will relapse following traditional treatment and rehabilitation within a year (McLellan et al, 2000). The ...
(hence no street value), it is favored by the criminal-justice system. Jails and prisons are increasingly offering inmates an injection of naltrexone; one dose is given at five weeks before release and another during the week of release with plans for ongoing treatment as an outpatient. Such ...