The fermentation culture of the engineered strain provided two isolates: the anticipated echinocandin E (1) and the surprising echinocandin F (2). Mass and NMR spectral data analysis revealed the structures of the previously unknown echinocandin derivatives in both compounds. Echinocandin E, in terms...
Mitochondrially targeted effects of berberine [Natural Yellow 18, 5,6-dihydro-9,10-dimethoxybenzo(g)-1,3-benzodioxolo(5,6-a) quinolizinium] on K1735-M2 mouse melanoma cells: Comparison with direct effects on isolated mitochondrial fractions. J. Pharmacol. Exp. Ther. 2007, 323, 636–649....