A sometimes forgotten disadvantage of metformin is its effect on vitamin B12absorption. Although the liability of metformin to lower vitamin B12levels has been well described,[3]interest in the need for monitoring for vitamin B12deficiency is more recent.[1,4,5,6] Vitamin B12deficiency is estimat...
Thirty three percent of the subjects were found to have borderline values of the serum vitamin B12 (148–220 pg/dl) while 22.5% had a clear, deficiency (levels less than 148 pg/dl). We found a highly significant inverse correlation between the dose and duration of metformin treatment ...
Medication interactions:There are several drug interactions to keep in mind if you take metformin. Although metformin itself is unlikely to cause hypoglycemia, taking it with otherdiabetes medicines, including insulin, can make blood sugar levels drop.12On the other hand, medicines that can increase ...
Evidence-based answer: Administration of routine vitamin B12 supplementation may protect against biochemical B12 deficiency in adults with type 2 diabetes who take metformin, but the clinical significance of this therapy is unknown (SOR: C, crosssectional and c...
Comparison of Serum Levels of Vitamin B12 and Folic Acid in Healthy Individuals and Type II Diabetic Patients Taking MetforminMansour, KarajibaniHossein, ZabihiFarzaneh, MontazerifarAlireza, DashipourJournal of Diabetes Nursing (2345-5020)