The t1/2 of tadalafil is 17.5 h and the tmax is approximately 2.0 h (range, 0.5–12.0 h; normalized for a 20 mg dose) in healthy volunteers. In men with ED treated with tadalfil, a significantly higher percentage of attempts at sexual intercourse was successful as long as 24–36 h ...
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Placebo-controlled trials have shown tadalafil to be safe and effective at doses of 5 to 25 mg for treating ED and doses of 10 to 20 mg for treating diabetes-related ED. Tadalafil is rapidly absorbed and patients have shown responsiveness (with multiple successful intercourse attempts...
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As a rule of thumb, Viagra and other medications have a shelf life of about 2 years. Viagra's expiration date is comparable to other common ED medications,
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The effectiveness and safety of avanafil for erectile dysfunction: a systematic review and meta-analysis. Curr Med Res Opin. 2014;30:1565–71. Article CAS PubMed Google Scholar Goldstein I, Lue TF, Padma-Nathan H, Rosen RC, Steers WD, Wicker PA. Oral sildenafil in the treatment of ...