In the present study, we observed low striatal MCT8 levels in the THRSP OE mice, confirming that the reduction of striatal T3 is a consequence of low MCT8, impairs brain TH uptake54. Also, functional deletion of MCT8 induces hyperthyroxinemia and upregulates Thrsp (Spot14) mRNA levels ...
B1: PROPOSED MECHANISMS WHEREBY THE T3 UPTAKE, DIALYZED FRACTION AND ANTIBODY EXTRACTED T4 NORMALIZE BINDING PROTEIN EFFECTS IN FREE T4 ASSAYS DO NOT EXPLA... B1: PROPOSED MECHANISMS WHEREBY THE T3 UPTAKE, DIALYZED FRACTION AND ANTIBODY EXTRACTED T4 NORMALIZE BINDING PROTEIN EFFECTS IN FREE T4 ...
But T3 uptake % is not very useful by itself. The T3 uptake test must be performed alongside a total T4 test in order to calculate free T4, also called the free T4 index. A high free T4 index may indicate hyperthyroidism while low levels may point to hypothyroidism [2]. The T3 uptake...
We measured T3 resin uptake (T3-RU) levels before the onset of treatment. The 17-item Hamilton Rating Scale for Depression (Ham-D-17) was administered before, during and after the eight weeks of treatment to assess changes in depressive symptoms. RESULTS: 16 patients (6.8 percent) had low...
TSH secretion as well as 123I-uptake was suppressed only partially by T3 (75 μg/day for a week). Close examination of thyroid functions and TRβ gene analysis were not possible in the family, except for paternal grandmother and one of her two sisters who showed no abnormality. The ...
The uptake of succinic acid in S1 segments was very low although we increased the concentration of [3H] succinic acid in the bathing medium by 2 fold. Therefore, reliable counts for this segment could not be obtained to determine kinetic parameters. The results suggest that the amount of NaD...
HepG2 cells have been used for investigating hepatotoxicity63and molecular mechanisms of AMA cytotoxicity7. HepG2 cells show a relatively low expression of OATP1B364and do not express NTCP65, while these two proteins are considered as main AMA uptake transporters. Therefore, HepG2 cells present...
BDE-47 induces metabolic dysfunction-associated steatotic liver disease (MASLD) through CD36-mediated increased fatty acid uptake and PPARalpha-induced abnormal fatty acid oxidation in BALB/c mice. Toxicol. Lett. 2024, 391, 100–110. [Google Scholar] [CrossRef] [PubMed] Chen, Y.; Yu, M....
The increase in Cc can be correlated to the extent of water uptake over the first day of immersion as follows. The water uptake is estimated by the Brasher–Kingsbury equation [20,21], which assumes that a coating layer of uniform thickness without swelling: 𝑉𝑤=100×log(𝐶/𝐶0)...
Human immunodeficiency virus (HIV) preexposure prophylaxis (PrEP) has high biomedical efficacy; however, awareness, access, uptake, and persistence on ther... DP Serota,ES Rosenberg,AM Lockard,... - 《Clinical Infectious Diseases》 被引量: 2发表: 2018年 BEING HIGH AND TAKING SEXUAL RISKS: ...