www.nature.com/scientificreports There are amendments to this paper OPEN Synthetic Tet-inducible artificial microRNAs targeting β-catenin or HIF-1α inhibit malignant received: 29 May 2015 accepted: 14 September 2015 Published: 06 November 2015 phenotypes of bladder cancer cells T24 and 5637 Yonghao...
Berberine can significantly inhibit the migration, invasion, and cell cycle progression of T24 and 5637 bladder cancer cells, promote their apoptosis, and down-regulate the expression of HER2/PI3K/AKT proteins. Berberine showed good docking with HER2 molecular...
Effect of CTP-mediated PTEN on 5637 bladder cancer cells and the underlying molecular mechanism Article Open access 10 December 2022 Implications of TERT promoter mutations and telomerase activity in urothelial carcinogenesis Article 29 March 2018 Downregulation of UPK1A suppresses proliferation and ...
Sirolimus inhibits the growth of bladder carcinoma cells and decreases their viability. Significant correlations were found between cell proliferation and sirolimus concentration (r = 0.830; p < 0.01) as well as between cell viability and sirolimus concentration (r = -0.896; p < 0.01). Conclusion...
Methods T24 bladder cells line were treated by 0.625, 1.25, 2.5,5,10 and 20 μmol/L sunibinib in 24, 48 and 72 h. The cytotoxic activity was analyzed by MTT. Results Sunitinib inhibited T24 cell proliferation in dose-dependent manner. When the plasma drug concentration exceeded up to 5...
关键词:膀胱癌;膀胱癌T24细胞;As2O3;APC;Apaf-1TheImpactofArsenicTrioxideonBladderCancerT24cellsApaf-1andAPCGeneExpressionObjective:AbstractToobservedtheimpactofarsenictrioxide(As2O3)ontheapoptoticproteaseactivatingfactor-1geneandadenomatouspolyposiscoli(APC)geneexpressioninbladdercancerT24cellsandinvestigatearsenic...
(▿) and primary bladder epithelial cells (□). PanelB: 5637 (▿), BFTC905 (□), HT1197 (○), and J82 (▵) were cell lines that were moderately inhibited. PanelC: relative sensitive cell lines include SCaBER (▵), TCCSUP (▿), and TSGH-8301 (□). These experiments were...
73.72%.Allinhibitionswereinatime—and—dosedependentmanners.AfterPKC412acting48hours.with theincreasingofconcentration,G,/Mperiodcellsfrom12.26% increasedto58.4l% ,showedtheG,/M periodcellblock.Conclusion:PKC412decreasedcellgrowth,invasionandinhibitedcloningformationof ...
δ-T3 induced cell cycle arrest in T24 (A, B) and 5637 cells (C, D) bladder cancer cells.Changxiao YeWei ZhaoMinghui LiJunlong ZhuangXiang YanQun LuCunjie ChangXiaojing HuangJi ZhouBingxian Xie
Short hairpin (sh)RNA targeting Notch1 was designed and constructed, and the T24 and 5637 BCCs were selected for transfection. The cells were classified into two groups: shRNA negative control (NC) and Notch1 shRNA. MTT and Transwell assays, and flow cytometry were performed to examine the ...