Multiple T2-hyperintensities on brain MRI had excellent diagnostic accuracy with the area under the ROC curve of 0.849, estimated on the whole group subjects aged 2–18 years. The diagnostic accuracy of T2-hyperintensities for NF1 were highest in the youngest age (2–8 years). At that age ...
Development of MRI T2 hyperintensities and cognitive functioning in patients with neuro- fibromatosis type 1. Acta Paediatr 2010;99:1657- 60Feldmann, R., Schuierer, G., Wessel, A., Neveling, N., Weglage, J. (2010). Development of MRI T2 hyperinten- sities and cognitive functioning in ...
White Matter Hyperintensities (WMHs) are suspected to be a direct manifestation of microvascular ischemic injury in the distribution of the penetrating arteriolar vessels on magnetic resonance imaging (MRI) and usually seen in elderly persons. Further study on this issue is important as it might relat...
By employing a novel voxel‐based model of the MRI signal, we test whether the extravasation of fluid and plasma proteins in the brain tissue and/or sulcal spaces can indeed explain the T2 FLAIR hyperintensities characteristic for ARIA〦. The modelled MRI voxel consists of myelin (my), ...
The “central vein sign” which is considered to be a MRI-detectable central vein inside white matter lesion identified as a hypointensity relative to the surrounding lesion on T2*-weighted images, has been introduced as a biomarker of inflammatory demyelination1,5. This central vein sign has be...
p09.5 diagnostic accuracy and clinical value of multiple t2-hyperintensities on brain mri in early diagnosis of neurofibromatosis type 1 (nf1) in children: a cross-sectional study-p09.5诊断的准确性和多个T2高信号1型神经纤维瘤病(NF1)在儿童早期诊断脑MRI的临床应用价值:横断面研究-知来论文发表中心...
P09.5 Diagnostic accuracy and clinical value of multiple T2-hyperintensities on brain MRI in early diagnosis of neurofibromatosis type 1 (NF1) in children: a cross-sectional studydoi:10.1016/s1090-3798(11)70236-7Z. SabolB. ReiM. Kovac Sizgoric...
Patients frequently exhibit T2-weighted hyperintensities called unidentified bright objects (UBOs) on brain magnetic resonance imaging (MRI), with unclear relationship to such cognitive disabilities. This study aimed to determine whether thalamo-striatal UBOs correlate with cognitive disturbances. Thirty-...
Lebrun C, Cohen M, Chaussenot A, et al. A prospective study of patients with brain MRI showing incidental T2 hyperintensities addressed as multiple sclerosis: A lot of work to do before treating. Neurol Ther 2014; 3: 123-132.Lebrun C, Cohen M, Chaussenot A, Mondot L, Chanalet S....
The present preliminary study is based on the longitudinal assessment of global and regional myelination of the normal adult human brain using fast macromolecular fraction (MPF) mapping. Additional markers were age-related changes in white matter (WM) hyperintensities on FLAIR-MR...