We explored patterns of recurrence in 1691 women with pT1mic/T1a/T1b, pN0 and M0 breast cancer according to four immunohistochemically defined tumour subtypes: (i) Luminal A (ER-positive, PgR-positive, HER2-negative and Ki-67关键词: Breast cancer Prognosis Tumour size Immunohistochemistry ...
Bauer, M. et al. Neutrophil gelatinase-associated lipocalin (NGAL) is a predictor of poor prognosis in human primary breast cancer.Breast Cancer Res. Treat.108, 389–397 (2008). ArticleCASPubMedGoogle Scholar Provatopoulou, X. et al. Circulating levels of matrix metalloproteinase-9 (MMP-9),...
PrognosisMastectomyMastectomy, SegmentalFemaleMeta-Analysis as TopicBackgroundConflicting data exist regarding optimum local therapy for early-stage triple-negative breast cancer (). We examined outcomes according to local treatment type in a large cohort of node-negative patients.MethodsA total of 1,242...
Cobleigh M.A.; Tabesh B.; Bitterman P.; Baker J.; Cronin M.; Liu M.; Borchik R.; Mosquera J.; Walker M.G.; Shak S.Tumor Gene expression and prognosis in breast cancer patients with 10 or more positive lymph nodes. Clin Cancer Res. 11:8623–31;2005. CrossRef Creton S.;Aard...
4T1 breast cancer cells were highly malignant based on obvious cell atypia (Fig. 3). In addition, the tumor necrotic area in group A was larger than the other three groups (Fig. 3). Both H&E and Masson staining showed irregular blood vessels, indicating a possible reduction in ...
ObjectiveTo investigate the value of exocrine LncRNA SPINT1-AS1 in diagnosis and prognosis of papillary thyroid carcinoma (PTC) . MethodsqRT-PCR was used to detect the expression of SPINT1-AS1 in PTC tissues, cell lines (TPC-1, BCPAP, K1 and IHH4) , serum exocrine bodies of patients and...
Metastases are the main cause of death in cancer patients, and platelets are largely known for their contribution in cancer progression. However, targeting platelets is highly challenging given their paramount function in hemostasis. Using a high-throughput screening and platelet-induced breast tumor cel...
including the reversal of tamoxifen resistance in estrogen receptor-positive breast cancer cells. However, few studies have investigated the anticancer effects of ACT001 in triple-negative breast cancer (TNBC), a highly aggr...
GFPT1 accelerates immune escape in breast cancer by modifying PD-L1 via O-glycosylation Background: Immune escape is one of the causes of poor prognosis in breast cancer (BC). Glutamine-fructose-6-phosphate transaminase 1 (GFPT1) is the first ......
Key Words CD44v6 Pancreatic cancer Metastasis Prognosis CD444分子是一种跨膜糖蛋白,是细胞粘附分子之一。因其介导着肿瘤细胞与宿主细胞和 细胞外基质的互相作用,而成为研究肿瘤转移及预后的热点。其中以含有外显子v6的CD44变 异体(CD44v6)与肿瘤的关系较密切[1,2]。本文应用免疫组化LSAB法检测47例胰腺癌组织 ...