Knee osteoarthritisT1ρ relaxationT2 relaxationMagnetic resonance imaging (MRI) T2 and T1ρ relaxation are increasingly being proposed as imaging biomarkers potentially capable of detecting biochemical changes in articular cartilage before structural changes are evident. We aimed to: 1) summarize MRI ...
In addition, no significant difference was seen between patients and control subjects in mean T2 relaxation times of patellar (33.4 vs 32.8 ms, p = 0.16) and trochlear cartilage (36.8 vs 36.6 ms, p = 0.70) (see Table 1). Conclusions: Our findings suggest that cartilage composition, ...
One of the first applications of T1ρ to magnetic resonance imaging (MRI) was investigated by Sepponen et al. [5] nearly 40 years ago, but the “spin-locking” concept is far older and embraces many elements developed in the mid 1950s [6]. While T1 and T2 relaxation times are essenti...
Roughly 20% of Americans run annually, yet how this exercise influences knee cartilage health is poorly understood. To address this question, quantitative magnetic resonance imaging (MRI) can be used to infer the biochemical state of cartilage. Specifically, T1rho relaxation times are inversely relate...
Poster: "ECR 2020 / C-03049 / Quantitative and qualitative evaluation of MRI T1-weighted sequence SMS TSE versus conventional TSE in knee imaging at 1.5T Tesla MRI scanner " by: " W. K. Chung 1, M. C. W. Liu2, R. Lee2, P. L. P. Chan2, W. W. Li1, C. T. Yuen2, J....
Proteoglycan depletion-induced changes in transverse relaxation maps of cartilage: comparison of T2 and T1rho. Acad. Radiol. 9, 1388–94 (2002). 16. Singh, A. et al. High resolution T1ρmapping of in vivo human knee cartilage at 7T. PLoS One 9, e97486 (2014). 17. Jin, T. &...
MRI was performed on a 3-Tesla system (Achieva 3.0 T, Quasar Dual, Philips Healthcare, Best, the Netherlands) using an 8-channel phased-array knee coil. Sagittal fat-suppression turbo spin echo T2-weighted images (FS-T2WI) were obtained using the following parameters: Repetition time/echo t...
Thirty-threecartilagespecimenswerecollectedfrompatientswhounderwenttotalkneearthroplastyduetosevereosteoarthritisandscannedwitha3TMRscannerforT1ρandT2quantification.NinespecimenswerescannedatthreedifferentorientationswithrespecttotheB0:0°,90°and54.7°.CorepunchesweretakenafterMRI.Collagenandproteoglycancontentswere...
Image registration improves human knee cartilage T1 mapping with delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) textabstractObjectives: To evaluate the effect of automated registration in delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) of the knee on the occurrence of movement artefacts on...
T2 relaxation, T1ρrelaxation, Articular cartilage, Knee osteoarthritis, Imaging biomarkerBackground Magnetic resonance imaging (MRI) T2 and T1ρ relaxation are increasingly being proposed as imaging biomarkers potentially capable of detecting biochemical changes in articular cartilage......