解析 cell本意是细胞,也有小单元的意思, prime意思是装填,准备好的意思 cell priming 的意思是:单元间准备/装填 分析总结。 cell本意是细胞也有小单元的意思结果一 题目 如何翻译t cell priming 答案 cell本意是细胞,也有小单元的意思,prime意思是装填,准备好的意思cell priming 的意思是:单元间准备/装填相关推荐 ...
CD8(+) T-cell priming and boosting: more antigen-presenting DC, or more antigen per DC? RNA transfection is a standard method to load dendritic cells (DC) with antigen for therapeutic cancer vaccination. While electroporation yields high trans... N Schaft,V Wellner,Christian Wohn… - 《Cancer...
Visualizing priming of virus-specific CD8+ T cells by infected dendritic cells in vivo. Nat. Immunol. 3, 265–271 (2002). Article CAS Google Scholar Ingulli, E., Ulman, D.R., Lucido, M.M. & Jenkins, M.K. In situ analysis reveals physical interactions between CD11b+ dendritic cells...
Using sorted naïve T cells and monocyte-derived dendritic cells pulsed with the test chemical or with chemical-protein conjugates, the successful priming of an antigen-specific T cell response is controlled after antigen-specific restimulation by cytokine readout. As the most specific response of ...
Thus, when classic MHC-I presentation and endosomal recycling compartment–dependent cross-presentation are impaired in dendritic cells, cell-autonomous noncanonical cross-presentation relying on ERGIC-derived MHC-I counters TAP dysfunction to nevertheless mediate CD8+ T cell priming. This is a preview ...
Thus, it is likely that the mechanisms for T cell dysfunction in HBV are unique and likely due to the peculiarities of hepatic T cell priming (Bénéchet et al., 2019) and the variable degrees of HBV antigen presentation that takes place in the liver (Bertoletti and Ferrari, 2016; ...
Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand LACK of functional expression of CD40 ligand (CD40L) on T cells results in hyper-IgM syndrome (HIGMl), a human immunodeficiency associated with a severely impaired humoral immune response that is consistent with defects in ...
(e) In vivo priming of CD8 T cells by the indicated CM conjugates. Note: use of the D-chirality amino acid (i.e. dSLVR) abrogates activity. Data on log scale are reported as geometric mean with 95% c.i. Comparison of multiple groups for statistical significance was determined using ...
CD4 T cell priming in dendritic cell-deficient mice. 来自 Oxford Univ Press 喜欢 0 阅读量: 50 作者:Paola,Castiglioni,Christina,Lu,David,Lo,Michael,Croft,Pierre,Langlade-Demoyen 摘要: Bone marrow (BM) chimeras (BMC) generated from mice carrying a null (-/-) mutation in the relB gene of...
other steps in the tumour immunity cycle may influence the effectiveness of immunotherapies based on checkpoint blockade. These include antigen presentation and T-cell priming, the capacity of tumour infiltration by functional CD8+T effector cells, as well as accumulation of immunoregulatory mechanisms th...