T-large granular lymphocytosis (T-LGL) in patients with chronic neutropenia: Epidemiological characteristics, clinical course and relation with clonal diseaseBackground: The disorders of T-LGL constitute a broad group of reactive or clonal conditions requiring further research attenti...
T cell large granular lymphocytosis (T-LGL) following autologous stem cell transplant (ASCT) has not often been reported. There have been three publications referring to T-LGL developing after allogeneic SCT and one case report of a case of T-LGL leukemia occurring after ASCT. Here, we report...
Howard MT, Bejanyan N, Maciejewski JP, Hsi ED. T/NK large granular lymphocyte leukemia and coexisting monoclonal B-cell lymphocytosis-like pro- liferations: an unrecognized and frequent association. Am J Clin Pathol 2010; 133: 936-41.
A 54-year-old woman presented with a severe autoimmune anemia, thrombocytopenia, neutropenia (Evans' syndrome), and CD8+ lymphocytosis, without signs of lymphadenopathy or splenomegaly. A diagnosis of T cell large granular lymphocyte (T-LGL) leukemia was made, based on cytomorphology, the typical...
TCRalphabeta+/CD4+ large granular lymphocytosis: a new clonal T-cell lymphoproliferative disorder. Large granular lymphocyte (LGL) leukemia is a well-recognized disease of mature T-CD8(+) or less frequently natural killer cells; in contrast, monoclonal e... Lima M; Almeida J; Dos Anjos Teixei...
Persistent LymphocytosisLarge Granular Lymphocyte LeukaemiaCentral Nervous System InfiltrationThe article presents a case-study of a 57-year-old man with a history of persistent lymphocytosis since 2007. He was diagnosed with T cell large granular lymphocyte (T-LGL) leukemia in 2011 and was referred ...
TCRalphabeta þ /CD4 þ large granular lymphocytosis: a new clonal T-cell lymphoproliferative disorder. Am J Pathol 2003; 163: 763–771. 16 Sandberg Y, Almeida J, Gonzalez M, Lima M, Barcena P, Szczepanski T et al. TCRgammadelta þ large granular lymphocyte leukemias reflect the ...
Define T cell. T cell synonyms, T cell pronunciation, T cell translation, English dictionary definition of T cell. n. Any of a class of lymphocytes, including the helper T cells and cytotoxic T lymphocytes, that form in bone marrow and mature in the thym
As of December 31, 2023, the FDA had become aware of 22 cases of T-cell cancers that occurred after treatment with CAR T-cell therapy. Malignancies that have been reported include T-cell lymphoma, T-cell large granular lymphocytosis, peripheral T-cell lymphoma, and cutaneou...
TCRalphabeta +/CD4 + large granular lymphocytosis: a new clonal T- cell lymphoproliferative disorderJ. Am J Pathol, 2003, 163(2):763-771.3 Olteanu H, Karandikar NJ, Eshoa C, et al. Laboratory findings in CD4(+)large granular lymphocytosesJ. Int J Lab Hematol, 2010, 3 26、2(1 Pt1...