It can increase the function of CAR-T cells and reduce manufacturing costs. The combination of CRISPR/Cas9 technology and CAR-T cell therapy may promote the development of this therapy and provide more effective and personalized treatment for cancer patients. Meanwhile, the safety...
Currently, innovative personalized approaches to immunotherapy are undergoing significant development. One such approach, adoptive T-cell therapy, which involves the infusion of engineered T cells into patients, has led to breakthroughs in the treatment of certain cancers [1,2]. This therapy entails t...
Currently, innovative personalized approaches to immunotherapy are undergoing significant development. One such approach, adoptive T-cell therapy, which involves the infusion of engineered T cells into patients, has led to breakthroughs in the treatment of certain cancers [1,2]. This therapy entails t...
T cellsadoptive cell therapycancersolid tumorsIn recent years, immunotherapy for the treatment of solid cancer has emerged as a promising therapeutic alternative. Adoptive cell therapy (ACT), especially T cell-based, has been found to cause tumor regression and even cure in a percentage of treated...
Huge advances have been made in the treatment of cancer with major breakthroughs coming from the development of immuno-oncology drugs such as check point inhibitors and T cell engagers. These drugs work by enabling the body’s own T cells to recognise and kill cancer cells. ...
Home Interaction of Immune and Cancer Cells Chapter Adoptive T-cell Immunotherapy: Perfecting Self-DefensesChapter First Online: 14 February 2022 pp 253–294 Cite this chapter Interaction of Immune and Cancer Cells Raphaëlle Toledano Zur, Galit Adler, Katerina Shamalov, Yair Tal, Chen ...
Chimeric Antigen Receptor T-cell (CAR-T) immunotherapy has revolutionized cancer treatment and made great breakthroughs in treating hematological malignancies, however its success in treating solid cancers remains limited mainly due to the lack of tumor-specific antigens. On the other hand, the ...
- 《Cancer Immunology Immunotherapy》 被引量: 29发表: 2014年 Canine cancer immunotherapy studies: linking mouse and human Despite recent major clinical breakthroughs in human cancer immunotherapy including the use of checkpoint inhibitors and engineered T cells, important chal... JS Park,SS Withers,...
Metastasis is a complex multi-step process in the biological behavior of tumor cells, which involves many factors, such as the ability of cancer cells to spread and invade, the entry of disseminated tumor cells (DTCs) into the circulatory system, and the entry of DTCs from the circulatory ...