Do helper T-cells cause B-cells to divide? How do helper T cells activate B cells? Do memory cells interact with helper T-cells? Are effector T-cells the same as helper T-cells? How is CTLA 4 activated in helper T-cells? What is the function of helper T cells?
Immune system - T Cells, B Cells, Activation: In its lifetime a lymphocyte may or may not come into contact with the antigen it is capable of recognizing, but if it does it can be activated to multiply into a large number of identical cells, called a clo
Adoptive transfer of chimeric antigen receptor (CAR)-T cells targeting antigens on lymphoid cells has revolutionized the treatment of advanced B cell malignancies7,8. Foremost anti-CD19 CAR-T cell therapies have proven remarkable efficacy in B-cell acute lymphoblastic leukemia (B-ALL), chronic lym...
Naïve cells are non-active lymphocytes that recognize and bind to specific antigens, become activated, and launch target attacks against foreign pathogens.
Dynabeads T cell activation and expansion kits have simple protocols to activate and expand your T cells or T cell subsets without compromising cell viability and functionality.
Specialized subpopulations of CD4+ T cells survey major histocompatibility complex class II–peptide complexes to control phagosomal infections, help B cells, regulate tissue homeostasis and repair or perform immune regulation. Memory CD4+ T cells are positioned throughout the body and not only protect...
Here we show that the failure of MIsa antigen to activate PI hydrolysis applies when resting B cells are used as antigen-presenting cells (APC). By contrast, when MIsa-bearing B cells are activated for 24h by exposure to lipopolysaccharide or, more importantly, to Mlsa-reactive T cells or ...
T cell autoimmunity is not elicited in similarly immunized B cell-deficient (mu MT) mice. The expression of the B7-2 and/or B7-1 costimulatory molecules, as well as specificity to a self Ag, cyt c, enabled B cells to activate T cells to proliferate and to express IFN-gamma, IL-4, ...
In the present study we sought to test the ability of GC B cells to activate T cells by antigen presentation and mixed lymphocyte reactions. The first set of experiments demonstrated that GC B cells obtained three or more weeks after immunization could induce IL 2 production by T cells only ...
Therefore, these observations suggest that professional APCs usually are required to activate naive T cells, and that B cell Ag presentation can only activate naive T cells under unusual circumstances. 展开 关键词: B-Lymphocytes Antigen-Presenting Cells T-Lymphocytes Animals Mice, Inbred BALB C Mice...