L. Jeffrey MedeirosThe University of Texas M.D. Anderson Cancer CenterSpringer New YorkVega, F T-cell/histiocyte-rich large B-cell lymphoma. In: Medeiros, LJ eds. (2011) Diagnostic pathology lymph nodes and spleen with Extranodal lymphomas. Amirsys, Altona, pp. 6-62-5...
Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) can show variable histological growth patterns and present remarkable overlap with T-cell/histiocyte-rich large B-cell lymphoma (THRLBCL). Previous studies suggest that NLPHL histological variants represent progression forms of NLPHL and THRLBCL tran...
T-cell lymphomas are rare and aggressive malignancies associated with poor outcome, often because of the development of resistance in the lymphoma against
The redirection of T cells has emerged as an attractive therapeutic principle in B cell non-Hodgkin lymphoma (B-NHL). However, a detailed characterization of lymphoma-infiltrating T cells across B-NHL entities is missing. Here we present an in-depth T cell reference map of nodal B-NHL, base...
Reactive T cells by flow cytometry distinguish Hodgkin lymphomas from T cell/histiocyte-rich large B cell lymphoma doi:10.1002/cyto.b.21261Cytometry. Part BWu, DavidThomas, AnjuFromm, Jonathan R.
Large cell morphology, CMYC+ tumour cells, and PD-1+ tumour cell/intense PD-L1+ cell reactions are important prognostic factors in nodal peripheral T-cell lymphomas with T follicular helper markers Yasuhito Mihashi, Shoichi Kimura, Hiromi Iwasaki, Yumi Oshiro, Yasushi Takamatsu, Shigeto Ka...
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IL-2 is a major growth factor for all T-cell subsets acting via a specific membrane receptor. To investigate its role in the pathogenesis of cutaneous T-cell lymphomas (CTCLs), we analysed the expression of high-affinity IL-2 receptors (IL-2Rs) on proliferating cells in these disorders. ...
Cutaneous T-cell lymphoma is a term that was created in 1979 at an international workshop sponsored by the National Cancer Institute (NCI) to describe a group of lymphoproliferative disorders characterized by localization of neoplastic T lymphocytes to t
(Th2) cells secreting IL-4, IL-5, and IL-13, which are critical mediators of extracellular parasite expulsion and mediate B cell class switch [27]. In recent years, the spectrum of CD4+ T cell subsets rapidly broadened by the identification of type 17 and type 22 helper (Th17, Th22)...