They play a central role in cell-mediated immu- nity and are distinguished by their T cell receptor (TCR), a special receptor on their cell surface. T cells originate in the bone marrow, mature in the thymus and travel in the blood to other lymphoid tissues, such as the tonsils, spleen...
Simple Plex assays on the Ella platform offer a rapid and precise assessment of secreted T cell activation markers.
Table 4. Multinomial logistic regression analyses of significant T-cell marker of Prefrailty and Frailty from stepwise forward selection Prefrailty Frailty OR 95% CI P-value OR 95% CI P-value Male sex 1.01 0.67 − 1.55 Age, years 1.01 0.98 − 1.04 Number of comorbidity 1.21 1.06 − ...
(I) The Kaplan–Meier survival curve with the log-rank test shows the survival difference between different TMGS and TMB groups. (J) Bar plot to show the difference in response to ICB treatment between different TMGS groups according to the TIDE algorithm. TMGS, T cell marker genes score;...
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We confirmed the prognostic efficacy of the T-cell marker gene signature using the AUC computed by the “survivalROC” program. In the Kaplan–Meier survival analysis, the log-rank test from the “survminer” R package was used to examine the statistical significance of differences. Finally, we...
Fig1.Immunecell atlas of the Hodgkin lymphoma microenvironment at single-cellresolution. 为了研究霍奇金淋巴瘤里免疫细胞的转录组数据,作者选择了22个经典霍奇金淋巴瘤患者的淋巴结进行单细胞转录组测序,包括12个NS亚型,9个MC亚型,和一个LR亚型,也对5个正常人的淋巴结进行了单细胞测序。根据已知的marker的表达情...
Since Helios expression is associated with T cell activation and cellular division, regardless of the cell subset involved, it does not appear suitable as a marker to distinguish natural and induced Treg cells. 展开 关键词: Animals Humans Mice T-Lymphocytes Cells, Cultured Transcription Factors DNA...
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Granzyme B is useful as a marker in the identification of NK/T-cell lymphomas. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin s Disease. 靶标信息 Granzyme B is a member of the granzyme serine prot...