“Over the past few years, we have seen the development of CAR T-cell therapy, which is a type of T-cell therapy where we collect the patient’s T cells and engineer them with a special receptor called the chimeric antigen receptor that targets an antigen on the lymphoma cell,” Zitella...
CAR-T cell therapy is becoming an interesting candidate in the treatment of cancer. Although most CAR-T cell therapy studies focus on the treatment of hematologic malignancies, such as lymphoma, with targeting CD19 antigen, demand for their application in the treatment of solid tumors in clinical...
The optimal treatment strategy for relapsed natural killer/T-cell lymphoma (NKTCL) remains largely unknown. We retrospectively reviewed the treatment modalities and prognosis of 56 relapsed NKTCL patients. Chemotherapy was the initial salvage treatment, followed by radiotherapy (RT) or autologous hematopoie...
“Peripheral T-cell lymphoma is an aggressive subset of non-Hodgkin lymphoma typically associated with a poor prognosis,” said Richard A. Miller, MD, co-founder, president, and chief executive officer of Corvus, in a news release. “For these patients, there is significant need for new the...
“Peripheral T cell lymphoma is an aggressive subset of non-Hodgkin’s lymphoma typically associated with a poor prognosis,” Richard A. Miller, MD, co-founder, president, and chief executive officer of Corvus, stated in a news release.1“For these patients, there is significant need...
n ≥ 25. A-MF, advanced-stage mycosis fungoides; BID, benign inflammatory dermatosis; CTCL, cutaneous T-cell lymphoma; E-MF, early-stage mycosis fungoides. Download: Download high-res image (489KB) Download: Download full-size image Figure 2. Receiver operating characteristic curve analysis of...
It has been established that MM patients with HRCAs generally have a worse prognosis, and that the prognosis of these patients varies depending on a number of factors, including the presence and the amount of specific genetic abnormalities as well as choice of therapy [18]. To this end, ther...
Radiotherapy and PGEMOX/GELOX regimen improved prognosis in elderly patients with early-stage extranodal NK/T-cell lymphoma The optimal treatment strategy for elderly patients with natural killer/T-cell lymphoma (NKTCL) remains to be established. A total of 63 elderly patients w... Xi-wen,Bi,Yi...
T-cell-based cellular therapy was first approved in lymphoid malignancies (B-cell acute lymphoblastic leukemia and large B-cell lymphoma) and expanding its investigation and application both in hematological and non-hematological malignancies. Two anti-BCMA (B cell maturation antigen) CAR (Chimeric An...
Rational Targets of Therapy in Extranodal NK/T-Cell Lymphoma. Cancers. 2023; 15(5):1366. https://doi.org/10.3390/cancers15051366 Chicago/Turabian Style Major, Ajay, Pierluigi Porcu, and Bradley M. Haverkos. 2023. "Rational Targets of Therapy in Extranodal NK/T-Cell Lymphoma" Cancers 15,...