惰性T淋巴母细胞增殖性疾病( indolent T lymphoblastic proliferations,iT-LBP)是一种罕见的在胸腺外淋巴组织或器官中出现T淋巴母细胞非克隆性增殖的疾病[1-2],其临床表现、病理学特点以及流式免疫表型与T淋巴母细胞白血病/淋巴瘤(T-lymphoblastic leukemia/lymphoma, T-ALL/LBL)相似,容易导致误诊,因此MICM多种手段...
T-cell acute lymphoblastic leukemia (T-ALL) is a highly aggressive neoplasm of lymphoblasts committed to the T-cell lineage. In 1994, the WHO Classification of Hematologic Malignancies defined T-ALL as precursor T lymphoblastic leukemia/lymphoblastic lymphoma underscoring the unity between the two ...
1. 定义 急性T 淋巴细胞白血病(T cell acute lymphoblastic leukemia, T-ALL)是急性淋巴细胞白血病(Acute lymphoblastic leukemia, ALL)的一种病理类型,是由T 系前体细胞在骨髓和胸腺发生恶性转化以及克隆性扩增引起的血液系统恶性肿瘤。 由于正常造血功能被破坏并且肿瘤...
Here we demonstrate that T cells expressing TCRs specific for peptides from the intracellular lymphoid-specific enzyme terminal deoxynucleotidyl transferase (TdT), presented in the context of HLA-A*02:01, specifically eliminate primary acute lymphoblastic leukemia (ALL) cells of T- and B-cell ...
Chidamide combined with a modified Bu-Cy conditioning regimen improves survival in patients with T-cell acute lymphoblastic leukemia/lymphoma undergoing allogeneic hematopoietic stem cell transplantation 译名:西达本胺联合mBuCy预处理...
acute lymphoblastic leukemia; acute myeloid leukemia; hypereosinophilic syndrome; γ/δ cells Abstract This case represents an example of an unusual T-cell lymphoblastic leukemia/lymphoma syndrome associated with eosinophilia and myeloid malignancy in a young boy. This case is one of only five reported...
Adult T-cell leukemia/lymphoma (ATL) is an aggressive peripheral T cell lymphoma associated with human T cell lymphotropic virus Type-1 infection (HTLV-1). From: Pharmacology & Therapeutics, 2022 About this pageAdd to MendeleySet alert
[5]WangP, Peng X, Deng X, et al. Diagnostic challenges inT-lymphoblastic lymphoma, early T-cell precursor acute lymphoblasticleukemia or mixed phenotype acute leukemia: A case report. Medicine(Baltimore). 2018, 97(41): e12743. END
T-lymphoblastic lymphoma/leukemia (T-LBL) is a neoplasm of immature lymphoid cells (lymphoblasts) committed to the T-cell lineage. The disease usually presents as an extramedullary tumor mass in the...Roberto N. MirandaThe University of Texas M.D. Anderson Cancer CenterJoseph D. Khoury...
T淋巴母细胞淋巴瘤/白血病(T lymphoblastic lymphoma/ leukemia,T-LBL/ALL)是起源于淋巴母细胞的高度侵袭性血液系统肿瘤,二者属于同一种生物学疾病。其临床表现为外周血及骨髓的侵犯、纵隔侵犯、肝脾淋巴结肿大,以及其他结外部位的受侵。疾病进展较快,诊断主要依赖于组织病理学、免疫表型、细胞遗传学等检查明确诊断。