Parker, D. C., T cell-dependent B cell activation. Annu. Rev. Immunol. 1993. 11: 331-360.Parker, D. 1993. T cell-dependent B cell activation. Ann. Rev. Immunol. 11(1): 331-360.Parker DC. T cell-dependent B cell activation. Annu Rev Immunol 1993; 11:331-60....
T-Cell/B-Cell Activation 产品编号产品名称产品包装产品价格操作 AF6387CCR2 Rabbit Polyclonal Antibody50μl 593.00元 AF6405CD27 Rabbit Polyclonal Antibody50μl 593.00元 AF7143Iba1 Rabbit Polyclonal Antibody50μl 593.00元 AF7146ICOS Rabbit Polyclonal Antibody50μl...
胸腺上皮细胞(thymic epithelial cell,TEC)以及其他胸腺基质细胞分泌细胞因子, 如干细胞因子(stem cell factor,SCF)和白细胞介素 -7(interleukin-7,IL-7)等,并表达 Notch 配体 DLL4(Notch ligand delta-like ligand 4,DLL4) 以及主要组织相容性复合体(major...
【4】Driving T cells into the TME is a gradual process (Figure 2): tumor cell death and antigen release, antigen-presenting cell (APC) processing and presentation of tumor antigens, and APC and T-cell interactions lead to T-cell priming...
应用:B细胞恶性肿瘤的潜在治疗靶点 来源:YTHDF2 promotes ATP synthesis and immune evasion in B cell malignancies. Cell, 2024 Dec 12. (图源:10.1016/j.cell.2024.11.007.[8]) 在《Cell》杂志上发表的研究中,科学家们揭示了YTHDF2蛋白在B细胞恶性肿瘤中的双重作用,即促进ATP合成和免疫逃逸。研究发现,YTHD...
We discovered that B-lymphocyte, T-lymphocyte, and plasma cell infiltration within the infarct progressively increases between 2 and 7 weeks after stroke. We then compared the B-lymphocyte response to stroke in WT, MHCII-/-, CD4-/-, and MyD88-/- mice to determine if B-lymphocytes mature ...
为探究Tmed4缺失对Treg细胞在体内对病理生理的影响，本研究利用实验性自身免疫性脑脊髓炎小鼠模型（EAE）、T细胞诱导的慢性肠炎模型（T cell-induced chronic colitis）以及MC38皮下瘤小鼠模型，揭示了Tmed4缺失会促进效应性T细胞，尤其是Th1和CD8+T细胞的活化，导致小鼠自身免疫性炎症的恶化和促进抗肿瘤免疫。图3. ROS...
T helper cell-driven activation of murine B cells has been shown to depend upon CD40-CD40 ligand (CD40L) interactions and a defined set of cytokines. These observations are primarily based on the use of conventional B cells obtained from the spleen. Therefore, it is presently unclear whether ...
[8] Neelapu SS, Locke FL, Bartlett NL, et al. Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma[J]. N Engl J Med, 2017, 377(26): 2531-2544. DOI:10.1056/NEJMoa1707447 [9] O'Rourke DM, Nasrallah MP, De...
Identification of a putative regulator of early T cell activation genes[J]. J Immunol,2010, 185(9):4972-4975. [2] Mognol GP,Carneiro FR,Robbs BK,et al. Cell cycle and apoptosis regulation by NFAT transcription factors :new roles for an old player[J]. Cell Death Dis,2016,7 :e2199....