The WBB Research Institute (WBBRI) recently hosted a two-part, 75-minute Demi-Colton Virtual Salon/Webinar on cell therapy and CAR-T, a breakthrough cancer treatment that modifies a patient’s own T-Cells to fight cancer. CAR-T and next generation cell ...
Moreover, we will describe the capability of these powerful CARs in targeting multiple tumor antigens, redirecting the CAR-T cells to specific target cells, incrementing the safety of CARs, and other advantages that lead to promising outcomes in cancer CAR-T cell therapy....
LOS ANGELES, April 23 (Xinhua) -- An advance in the breakthrough cancer treatment known as CAR T-cell therapy appears to eliminate its severe side effects, making the treatment safer and potentially available in outpatient settings, according to a new study of the University of Southern Californ...
Engineering for Success: Approaches to Improve Chimeric Antigen Receptor T Cell Therapy for Solid Tumors Article 23 February 2019 Introduction Autologous T cells redirected by chimeric antigen receptors (CARs) have been emerged as a new weapon for cancer therapy. The idea of constructing CARs by ...
Researchers at the National Cancer Institute-designated Montefiore Einstein Comprehensive Cancer Center (MECCC) have shown that a breakthrough therapy for treating blood cancers can be adapted to treat solid tumors—an advance that could transform cancer
CAR T cell therapy is an effective cancer treatment, but biological and manufacturing hurdles hamper its broad breakthrough. Although the first step towards automated manufacture of CAR cells has been taken, new technologies are needed to enable the treatment of large patient groups. ...
[7] SHAH N N,MAATMAN T,HARI P,et al. Multi TargetedCAR-T Cell Therapies for B-Cell Malignancies[J]. Frontiers inOncology,2019,9:146. [8] TAHMASEBI S,ELAHI R,KHOSH E,et al. Programmableand multi-targeted CARs: a new breakthrough in cancer CAR-Tcell therapy[J]. Clinical and Transla...
This therapy was designated as an annual scientific breakthrough in 2013 by Science magazine and has exhibited promising antitumor efficacy in recent years5,6,7. Cancer immunotherapies are categorized as immune checkpoint inhibitors (ICIs), adoptive cell therapies (ACTs), and tumor vaccines8,9. ...
Significant advances have been made in chimeric antigen receptor T (CAR-T)-cell therapy for the treatment of recurrent or refractory B-cell hematologic malignancies. However, CAR-T-cell therapy has not yet achieved comparable success in the management of
An advance in the breakthrough cancer treatment known as CAR T-cell therapy appears to eliminate its severe side effects, making the treatment safer and potentially available in outpatient settings, a new USC study shows.