AAV1/2-induced overexpression of A53T-alpha-synuclein in the substantia nigra results in degeneration of the nigrostriatal system with Lewy-like pathology and motor impairment: a new mouse model for Parkinson's disease Acta Neuropathol Commun, 5 (2017), p. 11 Google Scholar Kaushansky et al....
a set of sections for all the portions of the lumbar DRs was prepared and processed for molecular characterization of αβ T cells infiltrating into the lumbar DR leptomeninges. We utilized sequential double fluorescent immunolabeling with CD4/CD8 and αβTCR. In brief, sections were incubated fi...
In wild-type mice, gammadelta T cells were recruited to the site of tumor as early as day 3 after inoculation, followed by alphabeta T cells at day 5. We then used bone marrow chimeras and fetal liver reconstitutions to create mice with an intact gammadelta T cell reper...
tap coupler tap shift tap telocator alphanu tape bin tape clip tape deliverytd tape disc operating s tape driver tape drives streaming tape editor tape end-of-file prog tape handling option tape helper tape inputoutput swap tape insulated coil tape loosing tape operated typewri tape path tape ...
The ability of these vaccines to prevent or treat tumor (s.c. injected MCA205 sarcoma or B16 melanoma; i.v. injected B16-BL6) establishment/progression was then assessed. Results Immunization of C57BL/6 mice with mEphA2-derived peptides induced specific CTL responses in SPCs. Vaccination ...
The amino acid sequence alignment of those eight types, subtypes and isoform (TPalpha,beta, IP, EP1,2,3,4, FP, and DP1 in addition to another GPCR termed chemoattractant receptor-homologous molecule expressed on T helper 2 (TH2) cells (CRTH2 or DP2) that responds to PGD2 but belongs ...
We showed previously that NKT cell-deficient TCR Jalpha18(-/-) mice are more susceptible to methylcholanthrene (MCA)-induced sarcomas, and that normal tumo... Crowe,N. Y. - 《Journal of Experimental Medicine》 被引量: 943发表: 2005年 Activation of natural killer T cells by α-galactosyl...
Plasminogen, alpha-2 antiplasmin, tissue plasminogen activator (t-PA) and urinary type plasminogen activator are the main fibrinolytic components of plasma. The generation of plasmin is mainly regulated by processes involving t-PA and its counterpart plasminogen activator inhibitor type – 1 (PAI-1)...
a mouse homolog of human chemokine gro-alpha (CXCL1) IP-10: γ-interferon-inducible protein MCP-1: monocyte chemoattractant protein-1 Mig: monokine induced by γ-interferon MIP-1: macrophage inflammatory protein References Dudley ME, Wunderlich JR, Robbins PF, Yang JC, Hwu P, Schwartze...
Two rounds of amplification were used to generate the high-throughput sequencing library: the first to amplify all Igκ genes using primers Igκ Forward (Wang et al., 2000; 5′-agacgtgtgctcttccgatcGAYATTGTGMTSACMCARWCTMCA) and Cκ reverse (5′- acacgacgctcttccgatctGGATACAGTTGGTGCAG...