Cholesterol is an essential component of mammalian cells and is involved in many fundamental physiological processes; hence, its homeostasis in the body is tightly controlled, and any disturbance has serious consequences. Disruption of the cellular metabolism of cholesterol, accompanied by inflammation and...
Caching Database shardingDiscuss potential solutions and trade-offs. Everything is a trade-off. Address bottlenecks using principles of scalable system design.Back-of-the-envelope calculationsYou might be asked to do some estimates by hand. Refer to the Appendix for the following resources:Use...
To put an end to the political turmoil of recent years and the serious damage it has caused in Hong Kong, the CPC and the Chinese government have taken a series of major decisions, based on a clear understanding of the situation in the region. These include strengthening the central authorit...
Most often a type manifold registers as a primary contributor to supply the main body of the type. The JSON type manifold, for example, is a primary contributor because it supplies the full type definition corresponding with a JSON Schema file or sample file. Alternatively, a type manifold ...
With the increasing availability of large-scale biology data in crop plants, there is an urgent demand for a versatile platform that fully mines and utilizes the data for modern molecular breeding. We present Crop-GPA ( https://crop-gpa.aielab.net ), a c
Two examples of local coordinate systems are an airplane may have a local coordinate system with the x-axis aligned along the fuselage axis of the body and the y-axis pointing along the port wing. Choose the z-axis to form a right-handed coordinate system. a vehicle-mounted planar phased ...
Systems and methods are disclosed for providing user-friendly displays of data, particularly data displayed in a list. If a list item or other data is too wide to be displayed entirely in the horizontal space available in a single display area, then the data may be wrapped into an additional...
When a client mounts a remote file system, the client does not make a copy of the file system. Rather, the mounting process uses a series of remote procedure calls that enable the client to access the file system transparently on the server's disk. The mount resembles a local mount. ...
The editors of this journal generally will not consider changes to authorship once a manuscript has been submitted. It is important that authors carefully consider the authorship list and order of authors and provide a definitive author list at original submission. The policy of this journal around...
After sending the payment request to the PSP, the payment service keeps asking the PSP about the payment status. After several rounds, the PSP finally returns with the status. Short polling has two drawbacks: Constant polling of the status requires resources from the payment service. ...