Although the treatment of systemic sclerosis remains difficult, there are an increasing number of potentially effective regimens that are undergoing clinical investigations. A rational approach to therapy seems possible, based on a hypothesis of the pathogenesis of systemic sclerosis. Thus, there is ...
The use of JAK inhibitors in the treatment of progressive systemic sclerosis. J. Eur. Acad. Dermatol. Venereol. 32, e328 (2018). Google Scholar Sobanski, V. et al. Prevalence of anti-RNA polymerase III antibodies in systemic sclerosis: new data from a French cohort and a systematic ...
Systemic sclerosis (SSc) is a rare autoimmune connective tissue disease with multi-organ involvement, fibrosis and vasculopathy. Treatment in SSc, including early diffuse cutaneous SSc (dcSSc) and the use of organ-specific therapies, has improved, as evident from randomized clinical trials. Treatment...
(J VARGA, SECTION EDITOR) Current and Potential New Targets in Systemic Sclerosis Therapy: a New Hope Monique Hinchcliff1 & Steven O'Reilly2 Published online: 19 June 2020 # The Author(s) 2020 Abstract Purpose of Review Systemic sclerosis (SSc) is an autoimmune connective tissue disease in ...
Systemic sclerosis is a complex autoimmune disease characterized by a chronic and frequently progressive course and by extensive patient-to-patient variability. Like other autoimmune diseases, systemic sclerosis occurs more frequently in women, with a pe
More than half of patients received treatment with glucocorticoids at any point of the disease (68.31%), without gender difference. Conclusions Systemic sclerosis is less common in Latvia than in other countries and regions. Due to its location, the data from Latvia are consistent with a north-...
(PF) and involvement of other visceral organs.The treatment of systemic sclerosis is based on immunodepressant.Recently,with the development of related science,new immunodepressant,biological agent,and stem cell transplantation is used to treat systemic sclerosis,and gains significant effects.Latest study...
The assessment of disease activity in systemic sclerosis (SSc) is challenging owing to its heterogeneous manifestations across multiple organ systems, the variable rate of disease progression and regression, and the relative paucity of patients in early-phase therapeutic trials. Despite some recent succes...
Systemic sclerosis (SSc) is a severe autoimmune disease that is characterized by vascular abnormalities, immunological alterations and fibrosis of the skin and internal organs. The results of genetic studies in patients with SSc have revealed statistical
How can treatment of systemic sclerosis be improved?How can treatment of systemic sclerosis be improved?Editorial. Comments on ways in which systemic sclerosis can be improved. What systemic sclerosis is; Information on the findings of research into the disease.EBSCO...