Objective To examine parental influence on the development of systemic sclerosis (SSc; scleroderma). We designed 3 studies: mitochondrial inheritance, birth order (a possible surrogate marker for microchimerism), and paternal age at conception (a possible surrogate for telomere erosion) to examine ...
The term ‘scleroderma’ has been used since the mid-19th century but the first records date back to 1753, when Carlo Curzio described a 17-year-old girl with marked hardening of the skin all over her body [1]. Since 1980, scleroderma has been defined as a spectrum of diseases that con...
A large variation was observed in the mean length of hospitalization for Still’s disease in the group of patients with parasitic and respiratory diseases as compared to other comorbidities. The average length of hospitalization among persons with parasitic diseases was the longest in scleroderma and ...
SYSTEMIC sclerodermaINTERSTITIAL lung diseasesSURVIVAL rateIMMUNOSUPPRESSIVE agentsPULMONARY hypertensionIntroduction: Pulmonary arterial hypertension (PAH) is a leading cause of mortality in systemic sclerosis (SSc). This nationwide study aims to describe real world treatment characteristics and assess survival ...
SCLERODERMAStrokeCEREBROVASCULARAccidentAtrialFIBRILLATIONHypertensionAim:Theaimofthisstudyistodescribetheclinicalcharacteristicsofpatientswithadiagnosisofsystemicsclerosiswholatersufferastrokeandtoidentifyassociationsforthisrelationship.Background:Priorstudieshaveshowedanincreasedriskofcardiovasculardiseaseamongpatientswithchronic...
sclerodermasystemicdeathhospital chargeshospitalsThis study aimed to compare outcomes of systemic sclerosis (SSc) hospitalizations with and without lung involvement. The primary outcome was inpatient mortality while secondary outcomes were hospital length of stay (LOS) and total hospital charge. Data were ...
Systemic sclerosissclerodermaseasonepidemiology studymortalityadmissionObjectives: We aimed to determine rate of admission, mortality rate, and causes of death in systemic sclerosis (SSc) patients after stratifying by season.Method: A cross-sectional analysis was performed of patients over 15 in the ...
Thirty-four patients (33.6%) fulfilled a total of 39 ICD-10 psychiatric diagnoses. Total CIS-R score is significantly associated with duration of Scleroderma in univariate analysis ( p =0.019), but there was no significant association on a multivariate analysis. Depression [18.3% as against 5% ...
Scleroderma (Systemic Sclerosis): Classificiation, Subsets and Pathogenesis. J. Rheumatol. 1988, 15, 202–205. 2. Denton, C.P.; Khanna, D. Systemic sclerosis. Lancet 2017, 390, 1685–1699. [CrossRef] 3. Almeida, C.; Almeida, I.; Vasconcelos, C. Quality of life in systemic sclerosis...