Gene-level analysis of ImmunoChip or genome-wide association studies (GWAS) data has not been previously reported for systemic sclerosis (SSc, scleroderma). The objective of this study was to analyze genetic susceptibility loci in SSc at the gene level and to determine if the detected associations...
Overall, the high level of concentration and the dominance of a few large FIs highlight their potential systemic importance in the AFS. Table 1 reports certain financial soundness indicators of the AFS in 2007 and in 2019. The indicators illustrate the changes in financial soundness since the ...
This retrospective cohort study was conducted at a level-one trauma center from March 2014 to March 2023. The study enrolled patients aged 60 and above who had acute hip fractures and received orthopedic surgical treatment. The inclusion criteria specified patients who met these age and fracture re...
Mental models are described as being key to system transformation in systems thinking discourse, notably because they form the deepest level of a system82 and the strongest leverage point for change.83 Peter Senge highlights how difficult mental models are to change, as they generally exist beyond...
Crises like COVID-19 exposed the fragility of highly interdependent corporate supply networks and the complex production processes depending on them. However, a quantitative assessment of individual companies’ impact on the networks’ overall production
reconstruction under bootstrap for interbank networks is very important for concrete applications, since knowing even only the total number of interbank connections is practically impossible, while knowing the degree of a few banks is in many cases easier30. Using the above technique, the level of ...
which is used as index of systemic importance to assess systemic importance level of listed commercial banks,analyzes their dynamic characters and calculates their percentage contribution to systematic risk.Finally,the paper analyses factors influencing systemic importance of listed commercial banks from size...
We propose a hierarchical Marshall-Olkin model of countrywide systemic risk. At the lower level, we model the systemic risk of a crisis within the banking system (that we call "within" systemic risk) and at the higher level we model the probability of a joint default of the banking system...
We used the Search Tool for Retrieval of Interacting Genes/Proteins—STRING Version: 11.5 (http://string-db.org/)19 to assess the interactions of selected genes/proteins. We set the confidence level to 0.700 (high). We pulled interactions based on database, experiments, and co-expression. Re...
We also use optional cookies for advertising, personalisation of content, usage analysis, and social media. By accepting optional cookies, you consent to the processing of your personal data - including transfers to third parties. Some third parties are outside of the European Economic Area, with...