In vitro test system to evaluate xenobiotics as immune-modulators of drug transport and metabolism in human hepatocytesA method for evaluating in vitro the effect of a xenobiotic (e.g., a drug) on drug metabolism in hepatocytes. The kit comprises a first culture of hepatocytes, a portion of ...
as they are genetically encoded and recombinantly expressed. Accordingly, ELPs are widely used in the field of designing targeted biomolecules and in drug transport [74,103].
As a specific method of drug delivery methods, for example, guidance to the target site using supports (carriers) is being studied and this method is to load drugs onto supports that tend to concentrate in the target site and thereby make the supports transport the drugs to the target site....
The fundamental function of CVS is to transport substances to and from all parts of the body. The heart is the major pumping organ, pressurizing blood for circulation through the blood vessels; blood is propelled away from the heart in the arteries and returns to the heart through the veins...
skin properties allow the transport of a limited number of agents through passivetransdermaldelivery; for example, small lipophilic APIs, when dosage and consistency of release are not critical, are poised for transcutaneous delivery. Achieving sufficient drug absorption can prove to be a challenge for...
The brain is known to contain many peptides of diverse molecular weight and complexity. The larger ones contribute to the structure and to the enzymatic machinery essential for the metabolism of this complex organ. Smaller ones are hormones and some may be involved in the formation of long-term...
could be used to investigate the peripheral vs. CNS action of drug molecules such as opioids. To limit BBB penetration, a drug molecule is typically modified to increase its size and hydrophilicity. However, this often adversely affects the potency and pharmacokinetic properties of the drug ...
M. et al. The anandamide transport inhibitor AM404 activates vanilloid receptors. Eur. J. Pharmacol. 396, 39–42 (2000). Article CAS PubMed Google Scholar Högestätt, E. D. et al. Conversion of acetaminophen to the bioactive N-acylphenolamine AM404 via fatty acid amide hydrolase-...
Terpenoid transport in plants: how far from the final picture? Plants-Basel 12, 634 (2023). Article CAS PubMed PubMed Central Google Scholar Wittstock, U. & Gershenzon, J. Constitutive plant toxins and their role in defence against herbivores and pathogens. Curr. Opin. Plant Biol. 5, ...
Transport Package Carton or Wooden Cases Trademark ICEN Origin Guangzhou China Production Capacity 2000 Sets/Month Product Description IN-C006-1 cheap medical ecg handheld patient monitoring system patient monitor for hospital ICU Product Description F...