Purpose The aim of this study was to determine the stability of warfarin oral suspension in Syrspend in order to establish a shelf-life for the preparation after manufacturing. Material and methods 6 oral suspensions were prepared, using coumadine 5 mg tablets and Syrspend SF-PH4, packaged in...
The aim of this study was to determine the stability of 5 mg/mL prednisone oral suspension in a commercial compounding excipient: Syrspend® SF PH4. Methods Three batches of oral suspensions were prepared, using micronized prednisone and Syrspend® SF PH4. They were packaged in amber ...
Purpose The aim of this study was to evaluate the physicochemical stability of 5 mg/mL oxybutynin oral suspension in commercial compounding excipient Syrspend. Material and methods An oral suspension was prepared using oxybutynin powder and Syrspend, packaged in amber vials, to protect from light, ...
SF PH4. Methods Three batches of oral suspensions were prepared, using micronized prednisone and Syrspend® SF PH4. They were packaged in amber glass vials and stored at room temperature. On day 0, 1, 4, 10, 30, 60 and 90, we observed physical and chemical stability (pH measurement,...
For the first time, a stability-indicating LC-MS method has been developed to define the stability of IDB suspensions in SyrSpend Sugar-Free Unflavored (Fagron), a carrier phase formulated for setting up suspensions of active pharmaceutical ingredients (APIs) insoluble ...
Stability data of extemporaneous oral suspension of pentobarbital in Syrspend SF Alka for imaging sedation procedureImagingOral suspensionPediatricPentobarbital sodiumSedationStabilityPentobarbital is used as an alternative in pediatric sedative imaging procedures. Pentobarbital is only available as pharmaceutical ...
Preparation and physicochemical stability of 50 mg/mL hydroxychloroquine oral suspension in SyrSpend() SF PH4 (dry)HydroxychloroquineOral suspensionSARS-CoV-2 infectionStability-indicating assayIn the context of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, hydroxychloroquine ...
Zonisamide 10 mg/mL in Ora-Sweet:Ora-Plus (1:1) or SyrSpend SF PH4-Uses for this preparation are as an anticonvulsant and as adjunctive therapy for primary generalized tonic-clonic seizures.Method of Preparation: Calculate the quantity of each ingredient for the amount to be prepared. ...
Laboratory data show stability for amiodarone oral suspension at 5 mg/mL in Syrspend. However, this concentration is too low for important posologies. A more concentrated suspension is necessary (20 mg/mL). Purpose The aim of this study was to determine the physicochemical stability of ...
Conclusion This study showed that 100 mg/mL pyrazinamide oral suspension in Syrspend SF PH4 was stable for at least 90 days at room temperature, so we determined a shelf life of 90 days for this preparation. Further study, using a mass spectrometer method, will be conducted to confirm this...