Subsequently, serum syphilis screen was positive with reflex Rapid Plasma Reagin (RPR) titer at 1:64. CSF Venereal Disease Research Laboratory (VDRL) was positive at 1:64. In light of these results, the patient was transitioned to intravenous aqueous penicillin G 24 million units daily through ...
To ensure consistency and to avoid inter-lab- oratory variation [11], reverse-sequence syphilis testing was conducted at Johns Hopkins University (JHU) and included a screening chemiluminescence antibody test (DiaSorin, Saluggia, Italy) with reflex to Rapid Plasma Reagin (RPR) (Cardinal Health, ...
Although there is a significant decrease in cases of neurosyphilis, it is important to screen for it especially in HIV infected patients, due to the clinical and public health implications. Pneumonia: TB vs. PJP vs. Pulmonary Kaposi sarcoma vs. Bacterial pneumonia Our patient presented with ...
specimens (regardless of TPPA result), and reflexed to quantitative if reactive. In Zambia, initial syphilis screening was done using TPPA (without subsequent titration), and only TPPA-reactive specimens underwent further qualitative +/- quantitative RPR-testing. In South Africa, two HIV 4th and 3...
All pregnant women from January 2002 to December 2012 in 90 hospitals in Shenzhen (n = 2 441 237) were offered syphilis and HIV screening. A nontreponemal test was used to screen for syphilis, with reflex to treponemal testing if the test result was positive. Women testing positive...
treponemal IgM antibodies to the IgG/IgM screen had not significantly affected the sensitivity and specificity compared to the original IgG screen. But the addition of the comparable BioPlex RPR assay to the instrumentation significantly reduced the overall labor of syphilis screening and confirmation [...
Additionally, a qualitative RPR assay [Immutrep® RPR assay, Omega Diagnostics Ltd, Alva, UK] was performed on all serum specimens (regardless of TPPA result), and reflexed to quantitative if reactive. In Zambia, initial syphilis screening was done using TPPA (without subsequent titration), ...
Binding to cardiolipin is the basis of nontreponemal tests such as RPR and VDRL. These studies, however, are not specific to syphilis. False positive reactions can occur in the setting of pregnancy, autoimmune disorders, and other infections. These tests are used to screen for syphilis, and ...