the clinical symptoms, serology, and CSF values (CSF cell count or protein and a reactive CSF-VDRL) must be used in combination to determine the diagnosis. CSF examination is the only means by which
Results of nontreponemal testing may be reported as positive, also called reactive, or negative, also called non-reactive. If positive, the results may also indicate the amount of antibody present in the sample used for testing. A positive nontreponemal test result means that you may have syph...
is considered necessary to demonstrate a clinically significant difference between two nontreponemal test results that were obtained using the same serologic test. Nontreponemal tests usually become nonreactive with time after treatment; however, in some patients, nontreponemal antibodies can persist at a...
There are two possible outcomes: positive (reactive) or negative (non-reactive). A negative result means that there were no detectable traces of syphilis in your system. A positive result may indicate that you have syphilis. However, a positive diagnosis cannot be established until a TPA confirm...
An RPR test result can be eitherreactiveornonreactive,depending on if antibodies were detected. AnonreactiveRPR result means there were no antibodies to syphilis found in the blood sample. If you have been confirmed as nonreactive and you or your doctor still believe that you are at high risk...
Nowadays the significance of sera with isolated reactive treponemal chemiluminescence immunoassay (IRTCIA) results is being discussed. It is known that as a rule, women have this phenotype more commonly than men. Bopage et al. presented the results of the examination 19/63 (30.1%) subjects with...
The unheated serum reagin (USR) test, a standard qualitative test for syphilis, was evaluated for use as a quantitative test for the serodiagnosis of syphilis and as a means of determining the effectiveness of treatment. Tests were perfo... DE Pettit,SA Larsen,V Pope,... - 《Journal of...
Seroreactive infants and infants whose mothers were reactive at delivery should be followed up every 2-3 months until the test becomes nonreactive or the titre falls fourfold; the RPR/ VDRL should fall by 3 months of age and be nonreactive by 6 months of age if the infant was not infecte...
Several recent studies have shown that in immunocompetent patients and HIV-positive individuals who are being effectively treated for the HIV virus, a nonreactive RPR titer can reliably predict normalization of their CSF after treatment.[213][214] Therefore, the CDC no longer recommends repeat CSF...
All neonates with a reactive nontreponemal test should be followed serologically to monitor its resolution. If the nontreponemal test is nonreactive by the age of 6 months, no further evaluation or treatment is needed. If the neonate still has a reactive nontreponemal test, he is likely to be...