Synthetic cannabinoids are a large group of molecules that have been chemically synthesized and designed to interact with the human can- nabinoid receptors (CB1 and CB2). These are the same receptors to which delta9-Tetrahydrocannabinol (THC) binds in the CNS and organs.the Controlled Substance ...
2.2Availability and epidemiology of synthetic cannabinoids Syntheticcannabinoidsare sprayed on the dried plants and are usually smoked. The liquid oil form has also emerged for use in e-cigarettes or vape pens[1,34]. These substances are also mixed in counterfeit prescription pills; for example, fa...
EMCDDA-Europol Joint Report on a New Psychoactive Substance: 1-phenyl-2-(1-pyrrolidinyl)-1-pentanone (α-PVP). 2015. Available online: http://www.emcdda.europa.eu/publications/joint-reports/alpha-pvp_en (accessed on 1 September 2015). Patocka, J.; Kuca, K. Synthetic cannabinoids and “...
spice may now refer to any substance that can be smoked or inhaled, and that reacts on the body similarly to that of cannabis. It can be thought of as the street label for all synthetic cannabinoids (much like how “Band-Aid” brand is used to describe any type of simple bandage). ...
Cannabinoids is an ‘umbrella term’ describing any substance that modulates cannabinoid receptors and produces similar effects to those produced by the Cannabis plant, regardless of its origin. Depending on their source, cannabinoids are classified into three major classes: endogenous synthetized cannabinoi...
How did synthetic cannabinoids become novel drugs of abuse? The early 2000’s provided fertile ground for the emergence of new drugs of abuse. Existing drugs laws in the US centered around the Controlled Substances Act (CSA) from the 1970’s and an addendum to the CSA from the 1980’s cal...
Adamowicz P (2021) Blood concentrations of synthetic cannabinoids. Clin Toxicol 59:246–251. https://doi.org/10.1080/15563650.2020.1787429 Article CAS Google Scholar Nowak K, Adamowicz P (2021) Blood concentrations of new psychoactive substances belonging to benzodiazepine class. Forensic Toxicol. ht...
“The results are toxic and very dangerous, especially for vulnerable people — people with previous psychotic episodes — and the young,” said Liana Fattore, a chemist at Italy’s Institute of Neuroscience. Fattore, whose research specialty is cannabinoids and the new wave of THC mimics, says...
(CBD). However, CBD, like all natural cannabinoids, is a controlled substance in most countries, and its conversion into THC can be easily performed using common chemicals. We describe here the anticonvulsant properties of 8,9-dihydrocannibidiol (H2CBD), a fully synthetic analogue of CBD that...
Over the last decade, new psychoactive substances (NPS) have continuously been the focus of the international society since their emergence on the illicit